Can severe cirrhosis be cured?

Written by Si Li Li
Gastroenterology
Updated on December 11, 2024
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Severe cirrhosis is understood to refer to the decompensated stage of cirrhosis, which is the later stage of the condition, primarily characterized by the hardening of the liver.

Additionally, it presents a series of bodily complications such as ascites, as well as esophageal and gastric varices caused by portal hypertension. Sometimes, because of these varices, accidental rupture can occur during eating, leading to severe bleeding, which is a major upper gastrointestinal hemorrhage — a very dangerous complication. If this bleeding is not controlled, it can become life-threatening. Moreover, the skin may display spider nevi, and palmar erythema can appear on the hands; these are common manifestations and complications during the decompensated phase of cirrhosis.

Thus, cirrhosis is not curable. Treatment focuses on symptomatic relief to minimize discomfort caused by the symptoms, but the disease itself cannot be cured.

Other Voices

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Written by Wu Hai Wu
Gastroenterology
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What is the cause of a gurgling stomach in cirrhosis?

Cirrhosis patients experiencing gurgling noises in the abdomen may suffer from functional dyspepsia due to cirrhosis, leading to accelerated intestinal motility and the mentioned symptoms. It is also possible that patients with cirrhosis may concurrently have acute enteritis, causing these symptoms. If these symptoms occur, further comprehensive stool tests are necessary to determine whether the symptoms are caused by a viral or bacterial infection. Depending on the cause, different treatment measures should be adopted. Consider using montmorillonite powder to stop diarrhea and using Bacillus cereus, composite lactic acid bacteria, etc., to regulate the intestinal flora. Given the patient's cirrhosis, proactive liver treatment is essential. (Please use medications under the guidance of a doctor.)

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Written by Ye Xi Yong
Infectious Diseases
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How long can one live with hepatitis B-related cirrhosis?

We cannot give a definite answer on how long a patient with hepatitis B-related cirrhosis can live, as the life expectancy in late-stage cirrhosis is influenced by many factors including treatment measures, lifestyle adjustments, daily healthcare, and physical condition. Patients in the compensated stage of cirrhosis, if treated and the progression of cirrhosis is halted, with normal liver function and negative hepatitis B virus replication indicators, can work normally. In this state, the quality of life is good, and they can live to 70 to 80 years old. For patients in the decompensated stage of cirrhosis, if untreated and the cirrhosis is allowed to progress, about 70 to 80% may die within 5 years; however, aggressive treatment, including traditional Chinese medicine for liver fibrosis and cirrhosis, combined with antiviral treatment, bleeding prevention, liver protection, and liver transplantation, can significantly increase the survival time of patients.

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Written by Wu Hai Wu
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Will the platelet count be low in the early stages of cirrhosis?

The early stage of cirrhosis does not cause a decrease in platelets. Patients in the early stages of cirrhosis often have no obvious symptoms and may only exhibit fatigue, weight loss, jaundice, etc. However, once a patient with cirrhosis develops splenic hyperfunction, it can easily lead to a decrease in platelets, where the platelet count may drop to 100,000 per microliter. In such cases, it might be necessary to perform procedures like splenic embolization or splenectomy for antimicrobial treatment, and it is also important to prevent other complications of cirrhosis, such as esophageal and gastric varices, etc.

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Written by Li Hu Chen
Imaging Center
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Can cirrhosis be detected by ultrasound B?

If there are signs of hardening in the liver, which we call cirrhosis, an ultrasound, specifically a hepatobiliary ultrasound, can detect it. Especially in the middle and late stages, cirrhosis has some characteristic features on an ultrasound. First, one can observe the size of the liver. By the middle and late stages, the liver usually shrinks—a slight enlargement may occur early on, but it generally progressively diminishes. Additionally, the texture of the liver becomes harder, and through the ultrasound, the texture appears uneven with a bumpy feeling, or in other words, there can be seen a diffuse and uneven echo. However, for early-stage cirrhosis, a standard ultrasound may not be as sensitive. Nowadays, there are digital liver ultrasounds specifically designed to measure the degree of liver hardness, which provide objective data to help diagnose more sensitively and objectively. This method can definitely detect the condition.

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Is it okay not to remove the spleen for cirrhosis with splenomegaly?

Once cirrhosis patients are found to have splenic hyperfunction, in order to reduce the splenic hyperfunction and its phagocytic destruction of red blood cells, white blood cells, and platelets, the spleen must be dealt with. Traditionally, the treatment plan could involve surgically removing the spleen, also known as splenectomy. However, current treatment plans generally involve interventional methods. After multiple interventional embolizations, the spleen undergoes aseptic necrosis and is absorbed, thus improving the condition of splenic hyperfunction. Therefore, now in cases of cirrhosis with splenic hyperfunction, it is possible to treat without removing the spleen, using interventional methods instead.