Will the platelet count be low in the early stages of cirrhosis?

Written by Wu Hai Wu
Gastroenterology
Updated on January 08, 2025
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The early stage of cirrhosis does not cause a decrease in platelets. Patients in the early stages of cirrhosis often have no obvious symptoms and may only exhibit fatigue, weight loss, jaundice, etc. However, once a patient with cirrhosis develops splenic hyperfunction, it can easily lead to a decrease in platelets, where the platelet count may drop to 100,000 per microliter. In such cases, it might be necessary to perform procedures like splenic embolization or splenectomy for antimicrobial treatment, and it is also important to prevent other complications of cirrhosis, such as esophageal and gastric varices, etc.

Other Voices

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Written by Li Qiang
Intensive Care Unit
1min 5sec home-news-image

Which is more serious, liver failure or cirrhosis?

Liver failure refers to a functional impairment of the liver, which could be acute or chronic damage. For instance, it could be the end stage of chronic liver disease, or an acute condition such as hepatitis, or another acute liver lesion. Other common lesions may also cause a sudden abnormality in liver function, resulting in severe liver dysfunction. At this point, liver cirrhosis is a common cause of liver failure. For example, in the middle and late stages of liver cirrhosis, liver function is completely decompensated, meaning the liver can no longer maintain its basic normal functions, leading to liver failure. Therefore, liver failure is one of the major consequences of liver cirrhosis, but the two are distinct. Liver failure can also be caused by other reasons not related to cirrhosis. For example, acute ischemia in the liver, such as in shock patients, can lead to liver ischemia and subsequently liver failure. Liver cirrhosis is just one of the common causes thereof.

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Written by Wu Hai Wu
Gastroenterology
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In the early stages of cirrhosis, is there abdominal bloating and stomach pain?

Early-stage cirrhosis generally does not result in abdominal distension or stomach pain, and individuals in the early stages of liver cirrhosis might not exhibit any discomfort symptoms. However, if liver function reaches an advanced stage, complications like ascites associated with cirrhosis might occur, leading to abdominal distension. There might also be the occurrence of conditions like portal vein thrombosis, which can cause stomach pain, and possibly primary peritonitis, which can induce abdominal pain in patients. It is necessary to promptly identify the cause and adopt appropriate treatment measures. For example, if the stomach pain is caused by primary peritonitis, active anti-infection treatments should be applied.

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Written by Si Li Li
Gastroenterology
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Does early-stage cirrhosis hurt when pressed?

The anatomical location of the liver is covered by the ribs, so generally, the liver cannot be felt below the lower edge of the ribs, and since it is covered by the ribs, the liver cannot be pressed, hence there is no such thing as pain upon pressing. When we generally check for liver pain, we use percussion pain. By percussing the area of the liver, which is under the rib area, pain can be elicited in the liver, this is called percussion pain. The liver generally does not have tenderness because it simply cannot be pressed. Early stages of liver cirrhosis usually exhibit little to no pain sensation. However, some symptoms might appear during the decompensated phase, such as fatigue, weight loss, dull complexion, reduced urine output, edema, and spider angiomata, among other symptoms.

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Written by Si Li Li
Gastroenterology
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Can people with cirrhosis eat watermelon?

Patients with cirrhosis can eat watermelon, as it is typically consumed raw. Therefore, it is important to ensure cleanliness when eating watermelon, and one should chew slowly and thoroughly without overeating. Eating a moderate amount, preferably once or twice a week, is advisable. The dietary principle for patients with cirrhosis should focus on light and easily digestible foods, avoiding rough and hard textures. It is also crucial to avoid greasy, spicy, and irritating foods, and alcohol consumption must be strictly avoided. Hygiene in diet is important, and a high-protein diet is advisable. Regular, moderate exercise is recommended, but patients should not overexert themselves and should ensure sufficient rest.

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Written by Zhang Jian Kang
Infectious Disease
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Is hepatitis B cirrhosis contagious?

If hepatitis B is not well controlled, it can easily lead to the occurrence of cirrhosis. After the hepatitis B virus infects the human body, it causes repeated inflammatory damage to the liver, with recurring abnormalities in liver function. If during this period there is no formal antiviral treatment or lack of attention, it is very likely to lead to the development of cirrhosis. Once cirrhosis from hepatitis B occurs, it is generally irreversible. Cirrhosis due to hepatitis B is also an infectious disease, and its level of infectiousness mainly depends on the presence of the virus. If the viral load is positive, indicated by a positive HBV-DNA test, then it is infectious. If HBV-DNA is negative, then it is not infectious. Therefore, whether cirrhosis from hepatitis B is infectious primarily depends on the level of HBV-DNA.