Why does cirrhosis cause increasing weight loss and what can be done about it?

Written by Wu Hai Wu
Gastroenterology
Updated on December 09, 2024
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The reason why patients with cirrhosis are becoming thinner might be due to the decreased protein synthesis function of the liver after cirrhosis, leading to progressively lesser protein in the body, which results in the patient becoming thinner. It could also be because cirrhosis leads to poor digestion and absorption in patients, thereby reducing their absorption capacity and causing them to lose weight. Under these circumstances, some medications can be used for treatment, such as the infusion of albumin to supplement plasma proteins in the body. It is also important to actively treat the underlying cause of cirrhosis. For example, in the case of alcoholic cirrhosis, active efforts to abstain from alcohol and rehabilitative treatment are necessary. If the cirrhosis is caused by chronic hepatitis B virus infection, antiviral treatment should be administered.

Other Voices

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Written by Yang Chun Guang
Gastroenterology
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Is it okay not to remove the spleen for cirrhosis with splenomegaly?

Once cirrhosis patients are found to have splenic hyperfunction, in order to reduce the splenic hyperfunction and its phagocytic destruction of red blood cells, white blood cells, and platelets, the spleen must be dealt with. Traditionally, the treatment plan could involve surgically removing the spleen, also known as splenectomy. However, current treatment plans generally involve interventional methods. After multiple interventional embolizations, the spleen undergoes aseptic necrosis and is absorbed, thus improving the condition of splenic hyperfunction. Therefore, now in cases of cirrhosis with splenic hyperfunction, it is possible to treat without removing the spleen, using interventional methods instead.

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Written by Si Li Li
Gastroenterology
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What should be noted in the early stages of cirrhosis?

Cirrhosis is a disease characterized by diffuse fibrosis of the liver tissue, pseudolobules, and regenerative nodules. In China, it is mostly caused by chronic hepatitis B, with a small portion caused by chronic hepatitis C and alcoholic liver disease. What should be noted if someone has cirrhosis? Firstly, alcohol consumption should be restricted; regardless of whether the cirrhosis is alcohol-related, abstaining from alcohol is critical as it can further damage the liver cells; Secondly, a low-sodium diet is advised, meaning that salt intake should be reduced. Excessive salt can lead to fluid retention, resulting in ascites or edema; Thirdly, increase the consumption of vegetables and fruits and intake some high-quality proteins, such as beans or fish, but avoid raw seafood; Lastly, be cautious with the use of various medications. Drugs that cause liver damage should be avoided to prevent exacerbating cirrhosis.

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Written by Wu Hai Wu
Gastroenterology
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Do I need to take liver-protective medicine in the early stages of cirrhosis?

As for whether it is still necessary to take liver-protective medication in the early stages of cirrhosis, it depends on whether there is liver function impairment in patients with early-stage cirrhosis. If there is liver function impairment, such as elevated transaminases and bilirubin, then it is necessary to take some liver-protective medications. If liver function is normal, then it is sufficient to treat only the cause of the disease. For example, if cirrhosis is caused by chronic hepatitis B virus infection, but the patient's liver function is normal, then antiviral treatment alone is sufficient. If the cirrhosis is due to alcohol abuse, then strict abstinence from alcohol is required, and the condition can generally be stabilized.

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Written by Wu Hai Wu
Gastroenterology
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Is stool black in the early stages of cirrhosis?

In the early stages of cirrhosis, it is generally not common to see black stools. Patients in the early stages of cirrhosis may not experience complications associated with the condition, such as portal hypertensive gastropathy and esophagogastric varices, nor would they likely suffer from peptic ulcers, etc. However, if patients with cirrhosis do not actively seek treatment or undergo regular check-ups, they could develop conditions like peptic ulcers and possibly esophagogastric varices that may rupture and bleed, leading to black stools. If black stools occur, it is important to promptly complete an endoscopic examination to confirm the diagnosis. Under endoscopy, hemostatic treatment should be performed. It is also crucial to actively rehydrate, suppress gastric acid secretion, and protect the gastric mucosa among other treatments.

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Written by Wu Hai Wu
Gastroenterology
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Is the pain obvious in the early stages of cirrhosis?

In the early stages of cirrhosis, the pain is not very obvious. Patients in the early stages of cirrhosis may experience vague discomfort in the upper right abdomen, while others may never experience pain at all. Those in the early stages may also have symptoms such as belching, fatigue, acid reflux, jaundice, and dark urine. Further comprehensive auxiliary examinations are needed, such as liver function tests and abdominal imaging studies. At the same time, it is important to identify the cause of early-stage cirrhosis in patients as soon as possible and adopt appropriate treatment measures based on different causes. For instance, if it is caused by alcohol, then treatment should involve abstaining from alcohol.