Symptoms of lobular hyperplasia cancerization

Written by Lin Yang
Breast Surgery
Updated on September 02, 2024
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The symptoms of lobular hyperplasia transforming into cancer primarily include feeling a painless, solitary small lump in the breast. The lump is hard, with a rough surface, and its boundary with surrounding tissue is not clearly defined. It is not easily movable within the breast. As the lump progresses, it can invade the Cooper's ligaments, causing them to contract, and thus the skin over the lump often appears dimpled, known as the dimpling sign, which is an early sign of breast cancer. As breast cancer continues to develop, it can cause the breast to shrink, become harder, elevate the nipple, and may lead to the ducts being pulled, flattened, retracted, or even invaginated. The affected breast may also significantly enlarge over several months, causing an increase in volume and prominence.

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Written by Lin Yang
Breast Surgery
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Can ultrasonography detect lobular hyperplasia?

Lobular hyperplasia can be detected by ultrasound, appearing as heterogeneous hypoechoic areas on the ultrasound, and if cysts form, they appear as anechoic areas. The exact cause of lobular hyperplasia in the mammary glands is not very clear. It is currently believed to be related to elevated levels of estrogen caused by endocrine disorders, external environmental factors, work and living conditions, interpersonal relationships, and various other stressors that affect the psychological aspects, all of which can change the body’s internal environment. This in turn affects the function of the endocrine system, causing abnormal secretion of one or several hormones, ultimately disrupting the balance of hormone levels in the body, leading to increased estrogen, and causing mammary tissue hyperplasia.

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Will a bad mood make lobular hyperplasia worse?

Breast lobular hyperplasia can worsen with mood because it is related to elevated estrogen levels caused by endocrine disorders. External living conditions, work and life circumstances, interpersonal relationships, and various other stresses can cause neuropsychiatric factors, all of which can change the internal environment of the body. This, in turn, affects the function of the endocrine system, leading to abnormal secretion of one or several hormones. During the menstrual cycle, breast receptors and internal hormone levels change periodically. When the proportion of hormones in the body becomes unbalanced, an increase in estrogen levels and a decrease in progesterone secretion can lead to incomplete regression of breast hyperplasia after its increase, causing the exacerbation of breast hyperplasia.

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Does lobular hyperplasia usually cause pain?

The primary manifestation of mammary gland hyperplasia is cyclical swelling and pain in the breast, often occurring or worsening before menstruation and alleviating or disappearing after menstruation. Mild cases are noteworthy for the patient, while severe cases can affect daily life and work. However, some patients do not exhibit obvious cyclical changes; others may experience unilateral or bilateral breast swelling and pain or needle-like pain. The pain may extend to the shoulder, upper limbs, or shoulder-back area. A few patients may have nipple discharge. During physical examinations, nodular lumps of varying sizes, which are tough but not hard, can be felt in one or both breasts. Sometimes, these lumps are tender to touch, and their boundaries with surrounding tissues are unclear, but they do not adhere to the skin or chest muscles.

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The difference between breast cancer and lobular hyperplasia

The difference between breast cancer and lobular hyperplasia is as follows: Lobular hyperplasia primarily manifests as nodular lumps that can be felt within one or both breasts. These lumps vary in size, are tough but not hard, and sometimes tender to touch. The boundaries of the lumps with the surrounding breast tissue are not clear, but they are not adherent to the skin or chest muscles, sometimes presenting as areas of thickening with unclear boundaries. Breast cancer, on the other hand, appears as a solitary, painless lump that is hard as stone and can be round, oval-shaped, or irregular. It can grow large, has poor mobility, and can easily adhere to the skin and surrounding tissues. The growth of the cancerous lump is not related to the menstrual cycle or emotional changes, and it can grow rapidly in a short time. On a mammogram, breast cancer lumps may show tiny calcifications, abnormal vascular shadows, and spicules.

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Is hot compress effective for lobular hyperplasia?

Hot compresses for lobular hyperplasia have certain therapeutic effects, but the results may not be very significant. For patients with severe breast hyperplasia, breast supports can be used to lift the breasts, and Chinese medicine can be used for treatment. This involves soothing the liver and regulating qi, as well as balancing the thoroughfare and controlling vessels to alleviate pain and treat breast hyperplasia. Endocrine treatment is also an option, but it should be used as little as possible. For pre-menopausal women with very obvious pain, it can be taken before the onset of menstruation. Vitamin therapy can also be used, including vitamins B, C, E, etc. These have functions such as improving liver function, regulating sex hormone metabolism, and improving autonomic nervous functions, and can be used as adjunctive therapy for this condition. Vitamin E also has an effect in relieving pain.