Symptoms of lobular hyperplasia cancerization

Written by Lin Yang
Breast Surgery
Updated on September 02, 2024
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The symptoms of lobular hyperplasia transforming into cancer primarily include feeling a painless, solitary small lump in the breast. The lump is hard, with a rough surface, and its boundary with surrounding tissue is not clearly defined. It is not easily movable within the breast. As the lump progresses, it can invade the Cooper's ligaments, causing them to contract, and thus the skin over the lump often appears dimpled, known as the dimpling sign, which is an early sign of breast cancer. As breast cancer continues to develop, it can cause the breast to shrink, become harder, elevate the nipple, and may lead to the ducts being pulled, flattened, retracted, or even invaginated. The affected breast may also significantly enlarge over several months, causing an increase in volume and prominence.

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Written by Lin Yang
Breast Surgery
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Does lobular hyperplasia have classifications?

Breast hyperplasia grading and color Doppler mammography grading are the same: Grade 0 indicates incomplete assessment and requires further confirmation; Grade 1 is a negative result, meaning only the normal structure of the breast; Grade 2 are benign findings, indicating benign signs such as breast hyperplasia, breast cysts, and breast lipomas; Grade 3 refers to benign findings but with a 2% malignancy rate, such as fibroadenomas of the breast; Grade 4 is suspiciously malignant and biopsy is recommended; Grade 5 suggests a high likelihood of malignancy; Grade 6 is clearly malignant, needing pathological confirmation of malignancy.

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Written by Lin Yang
Breast Surgery
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Can mild pain from lobular hyperplasia be ignored?

For mild pain associated with lobular hyperplasia, it may not require intervention but regular follow-up is needed. For more pronounced symptoms, symptomatic pharmaceutical treatment should be administered. Supporting the breasts with a bra, using traditional Chinese medicine to soothe the liver, regulate qi, and harmonize the Chong and Ren meridians may alleviate the pain. Endocrine treatment is another option, though generally avoided if possible. However, for severe pre-menopausal pain, taking vitamins such as B, C, and E before menstruation can help as they improve liver function, regulate hormone metabolism, and enhance autonomic nerve function. Vitamin E also helps alleviate pain.

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Written by Jia Rui
Obstetrics and Gynecology
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What is bilateral mammary lobular hyperplasia?

Bilateral mammary lobular hyperplasia is a type of abnormal proliferative disease of the breast tissue. Patients with mammary hyperplasia primarily experience breast pain and have breast lumps, and it is a benign disease. This condition is caused by an imbalance in ovarian endocrine levels, changes in hormone levels in the body, and an increase in estrogen levels, leading to excessive proliferation and incomplete restoration of breast tissue. It is common in clinical practice to examine breast diseases when breast pain and lumps are present.

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Written by Fan Hong Qiao
Breast Health Department
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What should I do about the pain from lobular hyperplasia of the breast?

Breast lobular hyperplasia accounts for more than two-thirds of female breast disease patients and can occur from youth to middle age. In the early stage of the disease, there is breast pain, followed by lumps, or pale yellow nipple discharge. Therefore, women should pay attention to preventing the occurrence of breast lobular hyperplasia. Traditional Chinese medicine believes that breast lobular hyperplasia is caused by liver Qi stagnation and phlegm and Qi stagnation, related to unhappy emotions and depressive moods. If there is a satisfying sexual relationship between spouses, including a coordinated and harmonious sex life, it can maintain a happy mood and smooth liver Qi. The Qi and blood in the collaterals will be harmonized and smooth, and the breast lobule will not easily proliferate. Therefore, we should adjust from life and diet, and of course, necessary medical treatment is essential.

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Written by Lin Yang
Breast Surgery
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What should I do if lobular hyperplasia recurs?

After the recurrence of lobular hyperplasia of the mammary gland, if there are significant symptoms, Chinese herbal medicine can be used to alleviate the pain through the method of soothing the liver and regulating the Qi, and harmonizing the Chong and Ren meridians. Endocrine treatment is also an option, but should be avoided if possible. However, it can be taken before menstruation if the pain is particularly severe in the pre-menopausal period. Vitamin therapy can also be used, including Vitamin B, Vitamin C, Vitamin E, etc., which have effects on improving liver function, regulating sex hormone metabolism, and improving autonomic nerve function. These can be used as adjunctive therapy for the disease. Some also believe that Vitamin E can relieve pain. Regular follow-ups with breast ultrasound and mammography are also necessary.