Symptoms of lobular hyperplasia cancerization

Written by Lin Yang
Breast Surgery
Updated on September 02, 2024
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The symptoms of lobular hyperplasia transforming into cancer primarily include feeling a painless, solitary small lump in the breast. The lump is hard, with a rough surface, and its boundary with surrounding tissue is not clearly defined. It is not easily movable within the breast. As the lump progresses, it can invade the Cooper's ligaments, causing them to contract, and thus the skin over the lump often appears dimpled, known as the dimpling sign, which is an early sign of breast cancer. As breast cancer continues to develop, it can cause the breast to shrink, become harder, elevate the nipple, and may lead to the ducts being pulled, flattened, retracted, or even invaginated. The affected breast may also significantly enlarge over several months, causing an increase in volume and prominence.

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Written by Lin Yang
Breast Surgery
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What should I do about lobular hyperplasia of the breast?

For cases with mild symptoms or less severe conditions, treatment is generally not necessary; regular follow-ups with breast ultrasound or mammography are sufficient. For those with pronounced symptoms, medication and symptomatic treatments can be given, as detailed below: Chinese herbal medicine can be used, treating breast hyperplasia through methods that soothe the liver, regulate qi, and harmonize the Chong. Endocrine treatments are also an option, though preferably avoided, but can be administered before menstruation for those who experience significant pain during the premenopausal period. Vitamin therapy, including vitamins B, C, and E, can improve liver function and regulate basal metabolism, as well as enhance the function of the autonomic nervous system, serving as supplementary medicine for this condition. Recently, vitamin E is also considered to have pain-relieving effects. For individuals with a family history of breast cancer, lesions confined to a part of the breast, or those who still have significant lumps after menstruation, it is recommended to conduct a puncture biopsy and consider surgical treatment if necessary.

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Written by Fan Hong Qiao
Breast Health Department
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What should I do about the pain from lobular hyperplasia of the breast?

Breast lobular hyperplasia accounts for more than two-thirds of female breast disease patients and can occur from youth to middle age. In the early stage of the disease, there is breast pain, followed by lumps, or pale yellow nipple discharge. Therefore, women should pay attention to preventing the occurrence of breast lobular hyperplasia. Traditional Chinese medicine believes that breast lobular hyperplasia is caused by liver Qi stagnation and phlegm and Qi stagnation, related to unhappy emotions and depressive moods. If there is a satisfying sexual relationship between spouses, including a coordinated and harmonious sex life, it can maintain a happy mood and smooth liver Qi. The Qi and blood in the collaterals will be harmonized and smooth, and the breast lobule will not easily proliferate. Therefore, we should adjust from life and diet, and of course, necessary medical treatment is essential.

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Written by Lin Yang
Breast Surgery
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Is lobular hyperplasia nodules serious?

Small hyperplastic nodules are generally not serious. If the nodules are between 0.2-0.4cm, we can treat them with traditional Chinese medicine, using methods to soothe the liver, regulate qi, and harmonize the thoroughfare and conception vessels to treat breast nodules; If the nodules are between 0.6-0.8cm, breast ultrasound determines them as benign. If the psychological burden is light, regular ultrasound examinations can be scheduled. If the psychological burden is heavy, the nodules can be removed by minimally invasive Mammatome rotation to achieve cure. If the nodules are larger than 1.0cm, it is recommended to first perform cytology aspiration and biopsy to prevent misdiagnosis. If determined to be benign, surgical treatment can be used; if malignant, a full-body exam is recommended to check for distant metastasis to formulate a surgical treatment plan.

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Written by Lin Yang
Breast Surgery
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Can grade II hyperplasia of small leaves become cancerous?

Fibrocystic change grade II generally does not become malignant. Fibrocystic change grade II refers to breast hyperplasia or benign tumors of the breast. It can be identified based on the typical symptoms of cyclic breast swelling and pain that worsens before menstruation and diminishes or disappears after menstruation. During physical examination, there are nodular masses of varying sizes accumulated inside the breast, which are firm but not hard, sometimes with tenderness. Ultrasound examinations show no masses, or mammography shows a cotton-wool appearance, which are main symptoms of breast hyperplasia, but the possibility of concurrent breast hyperplasia and breast cancer needs to be considered. On one hand, patients with significant breast hyperplasia should be closely followed up, advising them to return to the hospital for re-examination every two or three months; on the other hand, for those with obvious hyperplastic lumps or unclear boundaries in the thickened areas, it is recommended to perform a biopsy on suspicious lesions to prevent misdiagnosis.

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Written by Lin Yang
Breast Surgery
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Can ultrasonography detect lobular hyperplasia?

Lobular hyperplasia can be detected by ultrasound, appearing as heterogeneous hypoechoic areas on the ultrasound, and if cysts form, they appear as anechoic areas. The exact cause of lobular hyperplasia in the mammary glands is not very clear. It is currently believed to be related to elevated levels of estrogen caused by endocrine disorders, external environmental factors, work and living conditions, interpersonal relationships, and various other stressors that affect the psychological aspects, all of which can change the body’s internal environment. This in turn affects the function of the endocrine system, causing abnormal secretion of one or several hormones, ultimately disrupting the balance of hormone levels in the body, leading to increased estrogen, and causing mammary tissue hyperplasia.