Symptoms of lobular hyperplasia cancerization

Written by Lin Yang
Breast Surgery
Updated on September 02, 2024
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The symptoms of lobular hyperplasia transforming into cancer primarily include feeling a painless, solitary small lump in the breast. The lump is hard, with a rough surface, and its boundary with surrounding tissue is not clearly defined. It is not easily movable within the breast. As the lump progresses, it can invade the Cooper's ligaments, causing them to contract, and thus the skin over the lump often appears dimpled, known as the dimpling sign, which is an early sign of breast cancer. As breast cancer continues to develop, it can cause the breast to shrink, become harder, elevate the nipple, and may lead to the ducts being pulled, flattened, retracted, or even invaginated. The affected breast may also significantly enlarge over several months, causing an increase in volume and prominence.

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Written by Lin Yang
Breast Surgery
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Can ultrasonography detect lobular hyperplasia?

Lobular hyperplasia can be detected by ultrasound, appearing as heterogeneous hypoechoic areas on the ultrasound, and if cysts form, they appear as anechoic areas. The exact cause of lobular hyperplasia in the mammary glands is not very clear. It is currently believed to be related to elevated levels of estrogen caused by endocrine disorders, external environmental factors, work and living conditions, interpersonal relationships, and various other stressors that affect the psychological aspects, all of which can change the body’s internal environment. This in turn affects the function of the endocrine system, causing abnormal secretion of one or several hormones, ultimately disrupting the balance of hormone levels in the body, leading to increased estrogen, and causing mammary tissue hyperplasia.

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Written by Jia Rui
Obstetrics and Gynecology
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What is bilateral mammary lobular hyperplasia?

Bilateral mammary lobular hyperplasia is a type of abnormal proliferative disease of the breast tissue. Patients with mammary hyperplasia primarily experience breast pain and have breast lumps, and it is a benign disease. This condition is caused by an imbalance in ovarian endocrine levels, changes in hormone levels in the body, and an increase in estrogen levels, leading to excessive proliferation and incomplete restoration of breast tissue. It is common in clinical practice to examine breast diseases when breast pain and lumps are present.

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Written by Lin Yang
Breast Surgery
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Why are there lymph nodes under the armpit in lobular hyperplasia?

Breast lobular hyperplasia generally does not involve enlargement of the lymph nodes. The enlargement of lymph nodes can be physiological or pathological. Physiological enlargement is either congenital or caused by inflammation, whereas pathological enlargement is generally caused by breast cancer. Lymph nodes affected by breast cancer can be located and fixed in the armpit, and may also be palpable above or below the clavicle. Lobular hyperplasia is related to the levels of hormones in the body; it is not inflammatory, but mainly associated with increased estrogen levels. There may also be variations in the quality and quantity of estrogen receptors in the breast tissue components, leading to uneven development in different parts of the breast.

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Written by Lin Yang
Breast Surgery
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What does breast lobule feel like to the touch?

Fibrocystic breast changes may occur in one or both breasts, where palpable, nodular lumps of varying sizes can be felt. These lumps are firm but not hard, and sometimes painful. The boundary between the lumps and surrounding breast tissue is unclear, yet they are not adherent to the skin or chest muscles, sometimes appearing as unclearly bordered thickened areas. Lesions are more commonly located in the upper outer quadrant of the breast but can affect the entire breast. The lumps may enlarge during premenstrual or postmenstrual phases, but they typically reduce in size postmenstrually. Diagnosis can be confirmed through breast ultrasound and mammography. Breast ultrasound typically indicates proliferative breast tissue, showing areas of uneven, low echogenicity and, in cases of cysts, anechoic areas.

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Written by Fan Hong Qiao
Breast Health Department
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What medicine should be taken for mammary gland hyperplasia?

Simple lobular hyperplasia of the breast does not require medication or other treatments, just pay attention to maintaining a healthy lifestyle and regularly check the lobular hyperplasia in both breasts at the hospital to monitor any changes in the condition. After menopause, as the body's estrogen levels decrease, the lobular hyperplasia will gradually improve. Just pay attention to a regular lifestyle, and there is no special dietary requirements compared to others. If the pain is unbearable and severely affects daily life, under the guidance of a doctor, you can take some traditional Chinese medicines that soothe the liver and regulate qi, invigorate blood and resolve stasis, or use estrogen receptor antagonists, which prevent the estrogen receptors from exerting their physiological effects, thereby relieving symptoms.