Why are there lymph nodes under the armpit in lobular hyperplasia?

Written by Lin Yang

Breast Surgery

Updated on June 14, 2025

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Breast lobular hyperplasia generally does not involve enlargement of the lymph nodes. The enlargement of lymph nodes can be physiological or pathological. Physiological enlargement is either congenital or caused by inflammation, whereas pathological enlargement is generally caused by breast cancer. Lymph nodes affected by breast cancer can be located and fixed in the armpit, and may also be palpable above or below the clavicle. Lobular hyperplasia is related to the levels of hormones in the body; it is not inflammatory, but mainly associated with increased estrogen levels. There may also be variations in the quality and quantity of estrogen receptors in the breast tissue components, leading to uneven development in different parts of the breast.

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What should I do if lobular hyperplasia recurs?

After the recurrence of lobular hyperplasia of the mammary gland, if there are significant symptoms, Chinese herbal medicine can be used to alleviate the pain through the method of soothing the liver and regulating the Qi, and harmonizing the Chong and Ren meridians. Endocrine treatment is also an option, but should be avoided if possible. However, it can be taken before menstruation if the pain is particularly severe in the pre-menopausal period. Vitamin therapy can also be used, including Vitamin B, Vitamin C, Vitamin E, etc., which have effects on improving liver function, regulating sex hormone metabolism, and improving autonomic nerve function. These can be used as adjunctive therapy for the disease. Some also believe that Vitamin E can relieve pain. Regular follow-ups with breast ultrasound and mammography are also necessary.

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Symptoms of lobular hyperplasia cancerization

The symptoms of lobular hyperplasia transforming into cancer primarily include feeling a painless, solitary small lump in the breast. The lump is hard, with a rough surface, and its boundary with surrounding tissue is not clearly defined. It is not easily movable within the breast. As the lump progresses, it can invade the Cooper's ligaments, causing them to contract, and thus the skin over the lump often appears dimpled, known as the dimpling sign, which is an early sign of breast cancer. As breast cancer continues to develop, it can cause the breast to shrink, become harder, elevate the nipple, and may lead to the ducts being pulled, flattened, retracted, or even invaginated. The affected breast may also significantly enlarge over several months, causing an increase in volume and prominence.

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The difference between breast cancer and lobular hyperplasia

The difference between breast cancer and lobular hyperplasia is as follows: Lobular hyperplasia primarily manifests as nodular lumps that can be felt within one or both breasts. These lumps vary in size, are tough but not hard, and sometimes tender to touch. The boundaries of the lumps with the surrounding breast tissue are not clear, but they are not adherent to the skin or chest muscles, sometimes presenting as areas of thickening with unclear boundaries. Breast cancer, on the other hand, appears as a solitary, painless lump that is hard as stone and can be round, oval-shaped, or irregular. It can grow large, has poor mobility, and can easily adhere to the skin and surrounding tissues. The growth of the cancerous lump is not related to the menstrual cycle or emotional changes, and it can grow rapidly in a short time. On a mammogram, breast cancer lumps may show tiny calcifications, abnormal vascular shadows, and spicules.

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Can mild pain from lobular hyperplasia be ignored?

For mild pain associated with lobular hyperplasia, it may not require intervention but regular follow-up is needed. For more pronounced symptoms, symptomatic pharmaceutical treatment should be administered. Supporting the breasts with a bra, using traditional Chinese medicine to soothe the liver, regulate qi, and harmonize the Chong and Ren meridians may alleviate the pain. Endocrine treatment is another option, though generally avoided if possible. However, for severe pre-menopausal pain, taking vitamins such as B, C, and E before menstruation can help as they improve liver function, regulate hormone metabolism, and enhance autonomic nerve function. Vitamin E also helps alleviate pain.

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Mammary duct ectasia is classified into several stages and can be treated as follows:

The grading of lobular hyperplasia and the staging of color Doppler molybdenum target are the same, First is grade 0, which is unconfirmed and requires further confirmation. Grade 1 is a negative result, which is normal and does not require treatment. Grade 2 indicates benign lesions, such as breast cysts and lobular hyperplasia of the breast, which are 100% benign at the second level. Lobular hyperplasia can be treated with medication, and benign cysts can be regularly reviewed with color Doppler ultrasound or surgically treated if there is a psychological burden. Grade 3 is possibly benign with a 2% risk of malignancy, typically referring to fibroadenomas of the breast, which can be treated surgically. Grade 4 is suspicious of malignancy, and in such cases, biopsy is recommended to determine benignity or malignancy, with surgical treatment advised if malignant. Grade 5 is highly suspicious of malignancy, and in such cases, surgical treatment is recommended, such as modified radical mastectomy or breast-conserving surgery. Grade 6 is confirmed malignant with pathological evidence of breast cancer.