Will thyroid cysts become malignant?

Written by Chen Xie
Endocrinology
Updated on August 31, 2024
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The formation mechanism of thyroid cysts may be due to the expansive growth of nodules, which compresses the venous vessels causing circulatory disturbances. This leads to tissue ischemia and atrophic degeneration, resulting in congestion and edema. Fluid accumulates to form cysts. Cysts formed through regressive changes in nodules can involve the entire nodule turning cystic or only partial cystic changes, thus forming masses that are partly solid and partly cystic. In thyroid cancer, cysts can also form due to necrosis, hemorrhage, and liquefaction. Therefore, thyroid cysts can also be cancerous. For this reason, regular observation and follow-up of thyroid cysts are necessary. If there is any indication of malignant transformation in a thyroid cyst, timely treatment is required.

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Written by Chen Xie
Endocrinology
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How to treat thyroid cysts?

Treatment of thyroid cysts generally does not require special treatment, just regular monitoring of thyroid ultrasound and thyroid function. Thyroid function must be monitored for thyroid cysts. When thyroid function is reduced, hormone replacement therapy is needed. When thyroid function is hyperactive, anti-thyroid treatment is needed. If the patient's thyroid function is normal, only regular monitoring of thyroid ultrasound and thyroid function is required to understand changes in the size of the cyst. However, if the cyst is large enough to cause symptoms such as breathing difficulties or carotid ischemia, surgical treatment is recommended in a timely manner. Currently, radiofrequency treatment is also a new treatment method, which can be considered as an alternative option, but it is not recommended.

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Written by Zhang Li
Endocrinology
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What are the symptoms of thyroid cysts?

Thyroid cysts generally refer to a cystic mass found in the thyroid, typically containing a mixture of fluid or semi-solid fluid. The mass usually has clear boundaries and is painless. It can move up and down with swallowing, which distinguishes it from some subcutaneous nodules. Thyroid cysts generally do not show obvious symptoms or clinical signs and are mostly discovered when looking in the mirror or during a physical examination. However, larger thyroid cysts may cause compression symptoms, such as pressing backward against the trachea or esophagus, leading to symptoms like breathlessness and discomfort swallowing. A small portion may also exhibit signs of thyroid dysfunction, such as hyperthyroidism or hypothyroidism, although this is relatively rare in clinical settings.

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Written by Zhao Xin Lan
Endocrinology
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Is a thyroid cyst serious if it becomes malignant?

Thyroid cysts are generally benign lesions, so their malignancy rate is not high, and they generally do not become malignant. Thyroid cysts can be solitary or multiple, and usually grow slowly without any clinical symptoms. Routine monitoring is mainly based on color Doppler ultrasound to observe changes in the cysts. If the cyst shows calcification of the cyst wall or rapid growth, attention should be given to whether there are other changes or internal bleeding within the cyst. Timely surgical treatment can lead to a very good prognosis.

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Written by Luo Juan
Endocrinology
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Can thyroid cysts become cancerous?

Thyroid cysts can potentially become cancerous. Initially, thyroid cysts may arise from various thyroid diseases such as nodular goiter, Hashimoto's disease, thyroid adenoma, and thyroid follicular cancer, which form through degeneration, liquefaction, and hemorrhage. They are one of the common diseases of the thyroid. In the population, at least 4% of people can feel thyroid nodules larger than one centimeter. Among these nodules, about 5% to 20% are cystic. Statistics show that even benign lesions causing cysts have a 4%-5% chance of becoming cancerous when the diameter of the individual exceeds 4 centimeters. Therefore, thyroid cysts can potentially become cancerous.

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Written by Zhao Xin Lan
Endocrinology
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Will thyroid cysts recur after surgery?

Thyroid cysts refer to fluid-filled sac-like structures that occur in the thyroid gland. Typically, thyroid cysts do not exhibit any clinical symptoms. However, if they continue to grow, there is a risk of bleeding within the cyst. Therefore, when the cyst is larger than 3 centimeters, surgical treatment is often recommended. Generally, surgical removal is quite safe and reliable, and the prognosis after surgery is usually good with a low risk of recurrence. However, there is still a chance of recurrence, and if it recurs, surgery can be conducted again. Hence, thyroid cysts are relatively mild and benign lesions. If the cyst is smaller than 3 centimeters, alcohol sclerotherapy can also be performed.