Do you need to take medication for epilepsy long-term?

Written by Yuan Jun Li
Neurology
Updated on April 29, 2025
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Patients with epilepsy are clinically divided into primary and secondary types. Primary epilepsy is mainly treated with medication, and most patients require long-term use of anti-epileptic drugs to control seizures. Some patients can completely control the symptoms of epilepsy with medication; if they are seizure-free for three to five years, it is referred to as clinical cure, and they may discontinue the medication. For patients experiencing primary epilepsy seizures, treatment focuses on the cause of the condition, such as common diseases like cerebrovascular diseases, including cerebral hemorrhage, cerebral infarction, brain tumors, encephalitis, brain parasite infections, and cranial trauma. After the primary disease is cured, symptoms of epilepsy may be controlled in these patients. If some patients still experience epilepsy seizures after treatment, they should continue taking long-term oral anti-epileptic drugs to control the seizures.

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Written by Liu Shi Xiang
Neurology
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Why does epilepsy occur at night?

Epilepsy that occurs at night is called sleep-related epilepsy. There are many reasons for this phenomenon, such as excessive fatigue, irregular sleep, menstrual onset, anxiety, depression, and more. Additionally, some patients exhale more carbon dioxide during sleep, causing hyperventilation and internal environmental imbalances, which can easily lead to abnormal discharges of brain neurons. When some patients experience symptoms of epilepsy at night, timely intervention and treatment are needed. First, patients should develop a good lifestyle, go to bed on time, get up on time, avoid staying up late, and avoid excessive fatigue. Furthermore, targeted medication should be given to prevent the onset of the condition. Common medications include lamotrigine, levetiracetam, carbamazepine, and sodium valproate. Besides, patients also need to maintain a good mindset and avoid tense and anxious emotions that could exacerbate symptoms.

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Written by Zhang Hui
Neurology
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What medicine should not be taken for epilepsy?

Patients with epilepsy mainly rely on some internal medicine drugs for treatment. There are many drugs available today, many of which can effectively control the occurrence of epilepsy and improve the quality of life of the patients. However, it is also important to note that some drugs should not be taken in reduced quantities, Firstly, there are some drugs that affect the liver. Many drugs can impact the liver, and since many antiepileptic drugs are metabolized through the liver, combining them can increase the burden on the liver and even induce necrotic hepatitis, Secondly, it is necessary to choose the medication according to the type of epileptic seizures. For example, if it is a visual seizure, or a myoclonic seizure, then one should not take Phenytoin sodium and Carbamazepine, as these two drugs can potentially exacerbate myoclonic and visual seizures, Thirdly, patients with epilepsy should also avoid taking drugs that affect the metabolism of epilepsy medication. If used together, it can cause a reduction in the efficacy of the epilepsy drugs, easily triggering an epileptic attack, or even a prolonged state of epilepsy.

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Written by Yuan Jun Li
Neurology
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What are the symptoms of abdominal epilepsy?

Patients with abdominal epilepsy can experience abdominal pain, and some may show symptoms of bloating, nausea, and vomiting, as well as diarrhea. Abdominal epilepsy is a type of epilepsy, commonly seen in children and adolescents. The symptoms generally recur and last mostly from three to five minutes. If the symptoms last more than five minutes, it is usually called a status epilepticus, and some antiepileptic drugs can be used to control the seizures. After an epileptic episode, an EEG might show spike-and-wave patterns. If the EEG is normal, a dynamic EEG can be conducted, which might increase the positive diagnostic rate for patients.

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Written by Tang Bo
Neurology
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What is epilepsy?

Epilepsy is a common disease in neurology and includes many types, generally including primary epilepsy and secondary epilepsy. Primary epilepsy refers to cases where the cause is unknown, while secondary epilepsy has a clear cause. Common causes include developmental disorders of the cerebral cortex, tumors, and cerebrovascular diseases, traumatic brain injuries, and central nervous system infections, including encephalitis, meningitis. Cerebrovascular diseases such as cerebral hemorrhage and cerebral infarction can also induce epilepsy. Additionally, certain neurodegenerative diseases, such as motor neuron disease and late-stage Parkinson's disease can also trigger epileptic seizures. Patients with ischemic hypoxic encephalopathy and toxic encephalopathy may also experience epileptic seizures, and some systemic diseases may also lead to epileptic seizures.

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Written by Liu Shi Xiang
Neurology
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What are the prodromal symptoms of epilepsy?

The prodromal symptoms of epilepsy are diverse, generally involving movement, sensation, and mood. Some patients may experience transient numbness or weakness on one side of their body prior to a seizure, while others may have hallucinations and atypical mental or behavioral changes. However, these symptoms are not necessarily indicative of an impending seizure. When such symptoms occur, it is crucial to consider the possibility of an epilepsy attack, and patients should promptly visit the neurology department of a hospital for a thorough examination, including an electroencephalogram (EEG). If the EEG shows significant abnormalities such as spikes, sharp waves, slow waves, spike-and-wave complexes, or sharp-and-slow wave complexes, it suggests the potential for an epileptic seizure. In such cases, preventive medication should be administered promptly, such as carbamazepine or sodium valproate.