Are pituitary tumors prone to recurrence?

Written by Chen Yu Fei
Neurosurgery
Updated on February 04, 2025
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Pituitary tumors in the brain are benign tumors that grow slowly. When the tumor size is relatively small, there are generally no clear symptoms or signs, and most patients can work, live, and study like normal people. It is recommended to treat pituitary tumors with surgical methods. Most pituitary tumors are benign. If they can be completely removed through microscopic surgery, or through the transnasal transsphenoidal approach, minimally invasive surgery can achieve ideal treatment results and generally will not recur. However, for individual patients with pituitary tumors, if the tumor is malignant, it may easily adhere to surrounding tissues in the early stages, making it difficult to completely remove surgically, thus it is prone to recurrence.

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Written by Chen Yu Fei
Neurosurgery
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Is pituitary tumor surgery done under general anesthesia?

For patients with pituitary tumors, general anesthesia is typically recommended for surgery. Clinically, a combined inhalational and intravenous anesthesia approach is adopted for treatment. Before surgery, anesthesia induction is carried out to stabilize the patient, who then undergoes tracheal intubation for general combined anesthesia. As the surgery nears completion, appropriate medication may be used to help shorten the anesthesia process. After the surgery is fully completed, the patient is transferred to the recovery room. Once the anesthetic drugs are gradually metabolized and consciousness returns to clarity, the tracheal tube is effectively removed.

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Postoperative complications of pituitary tumor surgery

For patients with pituitary tumors, a range of complications, sequelae, or concomitant ailments can easily occur after surgery. For instance, postoperative sellar hematoma may occur, and some patients may even experience the rupture of a pseudoaneurysm. Additionally, some patients may repeatedly suffer from headaches, dizziness, nausea, vomiting, and weakness in the limbs after surgery, along with significant memory decline, reduced cognitive function—including calculating ability, and orientation in time, space, and person—gradually diminishing. These are considered postoperative sequelae of pituitary tumor surgery.

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Written by Chen Yu Fei
Neurosurgery
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Is a pituitary tumor scary?

For pituitary tumors, if not treated promptly and effectively, the continuous enlargement of the tumor often causes patients to experience recurring symptoms such as headaches, dizziness, nausea, and vomiting. Additionally, a series of endocrine hormone imbalances accompanying the tumor often manifest various symptoms and signs. When the pituitary tumor grows to a certain size, it can also potentially cause pituitary apoplexy. Therefore, it is advisable for patients with pituitary tumors to seek timely medical attention at local hospitals and undergo early surgical treatment. By opting for endonasal transsphenoidal surgery to completely remove the pituitary tumor, most patients can achieve very good treatment outcomes, with a gradual alleviation of existing symptoms.

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Written by Chen Yu Fei
Neurosurgery
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Is a pituitary tumor easy to treat?

Currently, the treatment technology for pituitary tumors is relatively mature. For early-stage pituitary microadenomas that are only a few millimeters in size, and where vision and visual fields are not yet affected, a definite diagnosis can be made. Under the surgical microscope, complete removal surgery is achievable, and it is possible to preserve the normal function of the pituitary gland. As surgical experience continues to increase, not only can tumors within the sella be removed, but even large adenomas or giant pituitary adenomas growing above the sella can be safely excised. Therefore, for patients with pituitary tumors, it is advisable to choose to visit a local hospital as early as possible and opt for a complete removal of the pituitary tumor through a transnasal transsphenoidal approach.

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Written by Chen Yu Fei
Neurosurgery
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What to do if a pituitary tumor recurs?

If a pituitary tumor recurs, there is no need to worry excessively. Instead, it is advisable to actively visit the local hospital for a cranial MRI with contrast to determine the specific location and severity of the recurrent pituitary tumor. Treatment plans should be decided based on the patient's condition. For patients who are eligible for surgery, it is recommended to opt for surgical removal of the pituitary tumor again. If the patient is elderly and frail and cannot withstand surgery, conservative treatment is recommended. Treatment can be carried out through medication or radiation therapy, among other methods, to help improve symptoms and enhance the quality of life.