Can pituitary tumors heal on their own?

Written by Chen Yu Fei
Neurosurgery
Updated on September 24, 2024
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Under normal circumstances, pituitary tumors generally do not heal spontaneously. Pituitary tumors are benign tumors and although they grow slowly, they tend to continue growing. When they enlarge to a certain extent, they produce a series of symptoms and signs, such as headaches behind the eye sockets, the forehead, and both temporal sides. If the tumor breaks through the sellar diaphragm, it might also affect the optic nerve, leading to decreased vision and visual field defects. Moreover, it can severely erode the pituitary gland, causing symptoms and signs like decreased pituitary function, endocrine hormone disorders, and bringing significant suffering to the patient.

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Written by Chen Yu Fei
Neurosurgery
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The difference between pituitary tumors and pituitary adenomas

The difference between a pituitary tumor and a pituitary adenoma mainly lies in the extent of the affected tissue involved. Generally, pituitary tumors may have a broader range than pituitary adenomas, meaning that pituitary tumors include pituitary adenomas. Normally, a pituitary adenoma specifically refers to tumors occurring in the anterior lobe of the pituitary gland, as this lobe primarily consists of glandular tissue. Meanwhile, the posterior lobe of the pituitary is mainly neurohypophysis. Therefore, tumors typically referred to as pituitary adenomas occur in the anterior lobe. If a tumor is in the posterior lobe, it cannot be called a pituitary adenoma, but it still falls under the category of pituitary tumors.

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Written by Chen Yu Fei
Neurosurgery
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Is a pituitary tumor serious?

Pituitary tumors are mostly benign. The tumors grow slowly, but due to their special location adjacent to the pituitary gland, when the size of the pituitary tumor increases to a certain extent, it will inevitably affect the pituitary, impairing its function and leading to pituitary dysfunction. This dysfunction manifests as endocrine hormonal imbalances, resulting in a series of symptoms and signs. Therefore, it is usually recommended to treat pituitary tumors surgically. Clinically, it is generally advised to choose the transnasal transsphenoidal approach for complete resection of the pituitary tumor.

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Written by Chen Yu Fei
Neurosurgery
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Is pituitary tumor surgery done under general anesthesia?

For patients with pituitary tumors, general anesthesia is typically recommended for surgery. Clinically, a combined inhalational and intravenous anesthesia approach is adopted for treatment. Before surgery, anesthesia induction is carried out to stabilize the patient, who then undergoes tracheal intubation for general combined anesthesia. As the surgery nears completion, appropriate medication may be used to help shorten the anesthesia process. After the surgery is fully completed, the patient is transferred to the recovery room. Once the anesthetic drugs are gradually metabolized and consciousness returns to clarity, the tracheal tube is effectively removed.

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Neurosurgery
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How long should one rest after pituitary tumor surgery?

For patients who have undergone pituitary tumor surgery, it is recommended that they rest for at least about six months. During this initial post-operative period, patients should be placed in an intensive care unit to monitor vital signs, with a focus on consciousness, pupils, awareness, and limb activity, including blood pressure, heart rate, respiratory rate, and blood oxygen saturation. Once the patient's condition stabilizes, they can be transferred to a regular ward for continued treatment. Patients should not engage in early ambulation to prevent complications such as cerebrospinal fluid rhinorrhea. During the recovery period, rest should be prioritized, and strenuous physical activity should be avoided. At the same time, appropriate nutritional support should be strengthened. Generally, with about six months of rest, the body will gradually recover.

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Written by Chen Yu Fei
Neurosurgery
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Pituitary tumor complications

For patients with pituitary tumors, it is common to see certain complications, especially post-surgery, such as hematoma in the sellar region, life-threatening nasal hemorrhage, pseudoaneurysm rupture bleeding, cerebrospinal fluid rhinorrhea, meningitis, reduced pituitary function, diabetes insipidus, as well as associated issues with fluid, electrolyte imbalance, and acid-base imbalance. Some patients may also experience rare complications like eye muscle paralysis and nasal septum perforation. Therefore, for patients with pituitary tumors, it is crucial to closely monitor any changes in their condition after surgery. If any abnormalities are found, a prompt re-examination with a head CT should be conducted to observe changes and provide appropriate treatment.