Is Hashimoto's thyroiditis hereditary?

Written by Chen Xie
Endocrinology
Updated on September 12, 2024
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Hashimoto's thyroiditis is an autoimmune thyroid disease and is not hereditary. However, it tends to cluster in families, meaning if one's parents have a history of Hashimoto's thyroiditis, their offspring have a relatively higher risk of developing the disease. However, this is not absolute heredity; it simply indicates a familial clustering tendency. Treatment for Hashimoto's thyroiditis is relatively effective. If hypothyroidism occurs, one only needs to take lifelong replacement therapy with levothyroxine to maintain thyroid function within the normal range, which has minimal impact on the body. Therefore, there is no need for excessive worry.

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Written by Li Hui Zhi
Endocrinology
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Can you get pregnant with Hashimoto's thyroiditis?

Hashimoto's thyroiditis can lead to pregnancy, but the prerequisite is that you must visit an endocrinology specialist before pregnancy to check your thyroid function, ensuring that the TSH (thyroid-stimulating hormone) is controlled below 2.5. This situation is suitable for pregnancy because if TSH is greater than 2.5, it is likely to have a certain impact on the fetus's intelligence. Therefore, if you have Hashimoto's thyroiditis and are planning to conceive, you first need to check the thyroid function. If this indicator is normal, then you can consider pregnancy.

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Written by Tang Zhuo
Endocrinology
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How is Hashimoto's thyroiditis treated?

Hashimoto's thyroiditis is a chronic autoimmune disease and is the most common form of thyroid inflammation clinically. It can be diagnosed through thyroid function tests, iodine-131 uptake tests, thyroid antibody tests, and ultrasound examinations. If there are changes in imaging or if serum anti-thyroglobulin antibodies and anti-thyroperoxidase antibodies are positive, a diagnosis can be confirmed. Regarding treatment, if thyroid function is normal in Hashimoto's thyroiditis, no treatment is necessary, but close monitoring and observation are advised. If Hashimoto's thyroiditis is accompanied by transient hyperthyroidism, symptomatic treatment with beta-blockers can be administered. If there is a decrease in thyroid gland function, thyroid hormone replacement therapy should be initiated, typically with levothyroxine tablets, until thyroid function tests return to normal. Additionally, daily care is important, such as avoiding high doses of iodine intake, maintaining regular sleep patterns, avoiding staying up late, maintaining a positive and optimistic mood, avoiding anxiety and stress, preventing common cold and trauma infections, and ensuring a balanced diet with high protein, low fat, high carbohydrate, and high vitamin content.

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Written by Li Hu Chen
Imaging Center
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Ultrasonic manifestations of Hashimoto's thyroiditis

Under ultrasound observation, Hashimoto's thyroiditis generally presents as a diffuse enlargement of the thyroid, often symmetrically, although there are cases of unilateral enlargement as well. Additionally, the surface of the thyroid appears irregular and nodular. The ultrasound often reveals uneven echogenicity in the gland, sometimes with nodular changes and unclear boundaries. However, the ultrasonographic characteristics of Hashimoto's thyroiditis are not particularly specific unless it's a typical case of the disease, which can be roughly diagnosed via ultrasound. For atypical or early cases of Hashimoto's thyroiditis, diagnosis typically requires thyroid function tests, known as the "thyroid function six-item test," which remains the gold standard for diagnosing Hashimoto's thyroiditis.

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Written by Chen Xie
Endocrinology
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Does Hashimoto's thyroiditis cause weight loss?

Hashimoto's thyroiditis is an autoimmune thyroiditis where autoantibodies within the body cause the destruction of thyroid follicular cells, leading to thyroid cell failure. During the course of Hashimoto's thyroiditis, hyperthyroidism may occur. Due to the destruction of thyroid follicles by autoantibodies, a significant release of thyroid hormones into the blood occurs, resulting in a hyperthyroid state. Therefore, symptoms such as weight loss, heat intolerance, and excessive sweating which are typical of hyperthyroidism may also appear in Hashimoto's thyroiditis. However, as the disease progresses, the condition gradually leads to decreased thyroid function.

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Written by Li Hui Zhi
Endocrinology
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Hashimoto's thyroiditis is an autoimmune disorder that attacks the thyroid gland, leading to hypothyroidism.

Hashimoto's thyroiditis, also known as chronic lymphocytic thyroiditis, is an autoimmune disease. Some patients with Hashimoto's thyroiditis have normal thyroid function and generally do not require treatment, but it is recommended to regularly review thyroid function and have thyroid ultrasonography. Some patients with Hashimoto’s thyroiditis may also suffer from hypothyroidism, which can manifest clinically as fatigue, constipation, and edema. If these symptoms are present, it is advisable to visit an endocrinology specialist promptly, complete thyroid function tests, and use thyroid hormone supplements under the guidance of a doctor.