How is Hashimoto's thyroiditis caused?

Written by Tang Zhuo
Endocrinology
Updated on May 13, 2025
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Hashimoto's thyroiditis is a chronic autoimmune disease and is the most common type of thyroiditis clinically. Its etiology is primarily immunological, as Hashimoto's thyroiditis is an autoimmune disorder. Therefore, patients can detect a high concentration of anti-thyroid antibodies through blood tests, such as anti-thyroglobulin antibodies and anti-microsomal antibodies. Additionally, genetic factors are involved, with about 50% of patients with Hashimoto's thyroiditis having a family history. Environmental factors, including radiation, infections, excessive dietary iodine, and selenium deficiency, can also lead to Hashimoto's thyroiditis. In recent years, the incidence of Hashimoto's thyroiditis has notably increased.

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Endocrinology
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Does Hashimoto's thyroiditis require treatment?

Treatment depends on the case. Currently, there is no cure for Hashimoto's thyroiditis, and the main goal of treatment is to correct secondary thyroid dysfunction and reduce significantly enlarged thyroids. Generally, for patients with mild diffuse goiter without obvious compression symptoms and no thyroid dysfunction, no special treatment is needed; follow-up observation is sufficient. For patients with significant thyroid enlargement and compression symptoms, treatment with levothyroxine may be used to reduce thyroid swelling. If the patient has hypothyroidism, thyroid hormone replacement therapy can be administered. (Medication should be administered under the guidance of a doctor.)

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Written by Chen Xie
Endocrinology
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Can Hashimoto's thyroiditis be cured?

Hashimoto's thyroiditis is an autoimmune thyroiditis where the body itself has autoantibodies that lead to the destruction of thyroid follicular cells, resulting in the failure of thyroid cells. Therefore, Hashimoto's thyroiditis can manifest as hyperthyroidism, euthyroidism, and hypothyroidism. Ultimately, Hashimoto's thyroiditis may develop into hypothyroidism. Hypothyroidism is proliferative and generally cannot be completely cured, but clinical remission can be achieved through oral administration of levothyroxine. However, Hashimoto's thyroiditis cannot be completely cured and requires lifelong replacement therapy.

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Written by Chen Xie
Endocrinology
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How to cure Hashimoto's thyroiditis?

Hashimoto's thyroiditis is characterized by autoimmune antibodies destroying the thyroid gland, leading to a gradual decline in thyroid function and manifesting symptoms of hypothyroidism. Currently, this disease is incurable. Treatment mainly includes restricting iodine intake to keep it within a safe range to prevent the progression of autoimmune destruction of the thyroid. Patients who only have thyroid swelling without hypothyroidism generally do not require treatment. However, once hypothyroidism occurs, it can be treated with levothyroxine to alleviate the symptoms of hypothyroidism. Nevertheless, current levothyroxine treatment cannot stop the progression of the disease. When the thyroid swells rapidly with local pain or compressive symptoms, treatment with glucocorticoids can be considered. However, if the symptoms do not improve or the compressive symptoms are significant, surgical treatment may be considered, although the likelihood of developing hypothyroidism post-surgery is higher.

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Written by Luo Juan
Endocrinology
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Can people with Hashimoto's thyroiditis eat lamb?

Currently, there is no evidence to suggest that patients with Hashimoto's thyroiditis cannot eat mutton, so it is permissible to eat mutton. Hashimoto's thyroiditis is a common autoimmune thyroid disease and the primary cause of hypothyroidism. Its onset is generally closely related to genetic factors, abnormal iodine metabolism, and immune function abnormalities. The pathological characteristics are mainly marked by significant infiltration of lymphocytes and plasma cells in the thyroid, as well as fibrosis of thyroid tissues. In terms of diet, patients with Hashimoto's thyroiditis need to strictly control their iodine intake.

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Written by Tang Zhuo
Endocrinology
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Is Hashimoto's thyroiditis severe?

Hashimoto's thyroiditis, also known as chronic lymphocytic thyroiditis, is a common type of autoimmune thyroid disease. Hashimoto's thyroiditis is the most common cause of hypothyroidism. If hypothyroidism caused by Hashimoto's thyroiditis is identified, long-term administration of levothyroxine can achieve good control. It is worth noting that the clinical manifestations of Hashimoto's thyroiditis are often atypical, or may coexist with other thyroid diseases, or other autoimmune diseases. Special attention needs to be paid to certain types of Hashimoto's thyroiditis. One such type is Hashitoxicosis, Hashimoto's pseudohyperthyroidism, or Hashimoto's thyroiditis accompanied by thyroid tumors, Hashimoto's encephalopathy, or Hashimoto's with proptosis. These special types require particular attention.