Does Hashimoto's thyroiditis require medication?

Written by Chen Xie
Endocrinology
Updated on September 04, 2024
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Hashimoto's thyroiditis refers to the destruction of thyroid tissue by autoimmune cells. Therefore, during the course of the disease, three states of thyroid function can be manifested: hyperthyroidism, euthyroid state, and hypothyroidism. When the patient presents with hyperthyroidism, it is possible to treat with anti-thyroid drugs, but the dosage of the anti-thyroid drugs should be reduced. When thyroid function is normal, no special treatment is needed, and regular thyroid function testing is sufficient. When there is concurrent hypothyroidism, thyroid hormone replacement therapy is required to achieve clinical healing.

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Written by Chen Xie
Endocrinology
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Does Hashimoto's thyroiditis require medication?

Hashimoto's thyroiditis refers to the destruction of thyroid tissue by autoimmune cells. Therefore, during the course of the disease, three states of thyroid function can be manifested: hyperthyroidism, euthyroid state, and hypothyroidism. When the patient presents with hyperthyroidism, it is possible to treat with anti-thyroid drugs, but the dosage of the anti-thyroid drugs should be reduced. When thyroid function is normal, no special treatment is needed, and regular thyroid function testing is sufficient. When there is concurrent hypothyroidism, thyroid hormone replacement therapy is required to achieve clinical healing.

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Written by Chen Xie
Endocrinology
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Does Hashimoto's thyroiditis cause fever?

Hashimoto's thyroiditis belongs to autoimmune thyroiditis, where the body's own antibodies destroy the thyroid follicular cells, leading to apoptosis of thyroid cells. As the disease progresses, it may lead to hypothyroidism. Generally, Hashimoto's thyroiditis does not cause fever. If a patient with Hashimoto's thyroiditis experiences a fever, it is necessary to exclude other infectious diseases. If a patient with Hashimoto's thyroiditis has a fever, especially if there is significant tenderness in the thyroid area, it is necessary to exclude the possibility of concomitant subacute thyroiditis. If Hashimoto's thyroiditis is accompanied by subacute thyroiditis, small doses of hormones can be used for treatment. (Please use medication under the guidance of a doctor.)

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Written by Chen Xie
Endocrinology
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Hashimoto's thyroiditis diagnostic indicators

Hashimoto's thyroiditis is a type of autoimmune thyroiditis, which can present in various phases regarding thyroid function, manifesting as hyperthyroidism, hypothyroidism, or normal thyroid function. Therefore, for patients with Hashimoto's thyroiditis, it is necessary to check thyroid function to understand its status. Since Hashimoto's thyroiditis is an autoimmune thyroiditis, the thyroid peroxidase antibodies and thyroglobulin antibodies are generally elevated. Additionally, it is necessary to perform thyroid ultrasound to assess the thyroid's condition. For some difficult-to-distinguish patients, a further examination such as a 131I uptake test can be conducted, where the uptake rate in Hashimoto's thyroiditis is reduced. Even further, a fine needle aspiration biopsy of the thyroid can be performed, where we can observe significant lymphocyte infiltration.

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Written by Chen Xie
Endocrinology
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Is Hashimoto's thyroiditis hereditary?

Hashimoto's thyroiditis is an autoimmune thyroid disease and is not hereditary. However, it tends to cluster in families, meaning if one's parents have a history of Hashimoto's thyroiditis, their offspring have a relatively higher risk of developing the disease. However, this is not absolute heredity; it simply indicates a familial clustering tendency. Treatment for Hashimoto's thyroiditis is relatively effective. If hypothyroidism occurs, one only needs to take lifelong replacement therapy with levothyroxine to maintain thyroid function within the normal range, which has minimal impact on the body. Therefore, there is no need for excessive worry.

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Written by Chen Xie
Endocrinology
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How to cure Hashimoto's thyroiditis?

Hashimoto's thyroiditis is characterized by autoimmune antibodies destroying the thyroid gland, leading to a gradual decline in thyroid function and manifesting symptoms of hypothyroidism. Currently, this disease is incurable. Treatment mainly includes restricting iodine intake to keep it within a safe range to prevent the progression of autoimmune destruction of the thyroid. Patients who only have thyroid swelling without hypothyroidism generally do not require treatment. However, once hypothyroidism occurs, it can be treated with levothyroxine to alleviate the symptoms of hypothyroidism. Nevertheless, current levothyroxine treatment cannot stop the progression of the disease. When the thyroid swells rapidly with local pain or compressive symptoms, treatment with glucocorticoids can be considered. However, if the symptoms do not improve or the compressive symptoms are significant, surgical treatment may be considered, although the likelihood of developing hypothyroidism post-surgery is higher.