The difference between esophagitis and esophageal cancer.

Written by Si Li Li
Gastroenterology
Updated on April 15, 2025
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Esophagitis and esophageal cancer can be differentiated in the following aspects.

First, in terms of symptoms, esophagitis generally presents with symptoms such as acid reflux, heartburn, pain behind the sternum, belching, and upper abdominal pain. The main symptoms of esophageal cancer, on the other hand, are generally difficulty swallowing or pain when swallowing, and this symptom progressively worsens.

Second, regarding age, esophagitis can occur in any age group, while esophageal cancer is more common in elderly male patients.

Third, the best method of differentiation is through gastroscopy. Under gastroscopy, esophagitis can be diagnosed with findings such as mucosal erosion, congestion, and edema of the esophagus. Esophageal cancer, however, generally appears in the middle or upper or lower segments of the esophagus, and a diagnosis can be confirmed by performing a biopsy.

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What are the symptoms of esophageal cancer recurrence?

The symptoms of recurrent esophageal cancer are similar to those at its initial onset, primarily characterized by difficulties in swallowing and eating obstructions. Some may also experience nausea, vomiting, and reflux symptoms of the digestive tract. Of course, when recurrence occurs, if there are metastases to other distant organs, then clinical manifestations corresponding to those metastatic locations will appear. For example, if esophageal cancer metastasizes to the lungs, it could lead to coughing, expectoration, shortness of breath, or chest pain, and even clinical symptoms related to coughing up blood. If there is liver metastasis from esophageal cancer, symptoms might include abdominal pain, fatigue, poor appetite, and even ascites among other clinical manifestations related to liver metastasis.

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Typical symptoms of esophageal cancer

The most typical symptom of esophageal cancer is progressive difficulty swallowing, and a progressive sensation of swallowing obstruction is the most typical symptom. It's actually quite simple; the esophagus is akin to a water pipe or a tubular cavity. Esophageal cancer is like having a tumor grow inside this cavity, similar to something blocking the pipe, which causes the flow of water to be impeded. However, not only water passes through this esophagus, but also food. Therefore, if there's something inside the cavity, both water and food cannot pass through, leading to this difficulty swallowing and discomfort while swallowing.

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What are the symptoms of esophageal cancer?

The symptoms of esophageal cancer generally include progressive difficulty in swallowing, because the esophagus itself is a tubular cavity, similar to a water pipe. Esophageal cancer typically forms a tumor within this tubular cavity, creating an obstruction. Consequently, the most common symptoms include difficulty swallowing and a sensation of blockage during eating, since food must pass through the esophagus. Other symptoms can include nausea, vomiting, acid reflux, heartburn, and pain below the breastbone. Moreover, the difficulty in swallowing generally worsens progressively, as the tumor grows from small to large, increasingly narrowing the esophagus and exacerbating the swallowing difficulties.

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Written by Si Li Li
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The difference between esophagitis and esophageal cancer.

Esophagitis and esophageal cancer can be differentiated in the following aspects. First, in terms of symptoms, esophagitis generally presents with symptoms such as acid reflux, heartburn, pain behind the sternum, belching, and upper abdominal pain. The main symptoms of esophageal cancer, on the other hand, are generally difficulty swallowing or pain when swallowing, and this symptom progressively worsens. Second, regarding age, esophagitis can occur in any age group, while esophageal cancer is more common in elderly male patients. Third, the best method of differentiation is through gastroscopy. Under gastroscopy, esophagitis can be diagnosed with findings such as mucosal erosion, congestion, and edema of the esophagus. Esophageal cancer, however, generally appears in the middle or upper or lower segments of the esophagus, and a diagnosis can be confirmed by performing a biopsy.

doctor image
home-news-image
Written by Liu Liang
Oncology
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The main metastatic pathways of esophageal cancer

The main metastatic pathways of esophageal cancer include firstly, hematogenous spread, which can transfer to distant organs such as bones and the lungs or liver via the bloodstream. The second pathway is via the lymphatic system, which can lead to the metastasis of regional lymph nodes and other non-regional lymph nodes. For example, cervical esophageal cancer tends to metastasize to the supraclavicular and adjacent esophageal lymph nodes; in thoracic esophageal cancer, metastases may occur in the subcarinal, upper periesophageal, and lower periesophageal lymph nodes; metastasis can also be achieved through local spread and invasion of the tumor.