Gallbladder cancer skin itching area

Written by Liu Wu Cai
Hepatobiliary Surgery
Updated on February 22, 2025
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Patients with gallbladder cancer may develop obstructive jaundice as the tumor size increases, which can manifest as yellowing of the skin and mucous membranes, dark urine, and pale stools. Patients may also experience itching and discomfort. For these patients, the treatment effectiveness is generally poor, and gallbladder cancer is a type of malignancy that tends to metastasize and has a very poor prognosis. Once symptoms are prominent, treatment becomes relatively difficult and less effective. It is advisable for gallbladder cancer patients to undergo surgical resection as early as possible to improve their prognosis. However, the onset of gallbladder cancer is often insidious and frequently overlooked.

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Written by Liu Wu Cai
Hepatobiliary Surgery
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Early symptoms and warning signs of gallbladder cancer.

Patients with early-stage gallbladder cancer generally do not display specific symptoms or obvious precursors. Some patients may experience digestive symptoms such as abdominal bloating, indigestion, nausea, and vomiting, but these are often overlooked. Thus, by the time gallbladder cancer is diagnosed, it is usually at an advanced stage, where the pain becomes significant and is one of the main reasons patients seek medical attention. Additionally, some patients may experience weight loss and even develop cachexia. Gallbladder cancer is a highly malignant tumor with rapid progression and a tendency to metastasize to other parts of the body, resulting in a very poor prognosis. Therefore, once diagnosed with gallbladder cancer, it is crucial to complete relevant examinations, rule out any contraindications for surgery, and proceed with surgical removal as soon as possible.

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Written by Liu Wu Cai
Hepatobiliary Surgery
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Is gallbladder cancer prone to spreading?

Gallbladder cancer is a type of cancer that is prone to spreading and is of a higher malignancy level. It is difficult to detect in the early stages. Patients with gallbladder cancer may initially present with subtle right upper abdominal pain, which is often overlooked. Therefore, once diagnosed with gallbladder cancer, it generally has reached the mid to late stages. At this time, the patient's pain becomes significant, which is the primary reason for seeking medical attention. Gallbladder cancer progresses rapidly and is prone to metastasize to other locations, such as the liver, leading to liver dysfunction, jaundice, ascites, hypoalbuminemia, and more. Additionally, for gallbladder cancer, the treatment strategy emphasizes early surgical removal to achieve better therapeutic outcomes.

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Written by Liu Wu Cai
Hepatobiliary Surgery
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Can people with gallbladder cancer eat lamb?

Patients with gallbladder cancer can appropriately eat mutton, as mutton is a food high in protein, which can supplement the albumin needed by the human body and better improve the patient's resistance. However, patients with gallbladder cancer may experience discomfort such as pain in the upper right abdomen and may also encounter digestive symptoms like indigestion and bloating. Therefore, it is recommended for gallbladder cancer patients to consume foods that are easy to digest, which can reduce the burden on the gastrointestinal tract and facilitate recovery. Although mutton can be consumed, it should be eaten in small, frequent meals to prevent complications such as intestinal obstruction. Additionally, for the treatment of gallbladder cancer, surgical removal should be used as early as possible to achieve a cure, with earlier detection and treatment likely leading to a relatively better prognosis.

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Written by Shen Jiang Chao
Radiology
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MRI manifestations of gallbladder cancer

The manifestations of gallbladder cancer on MRI primarily include significant thickening of the gallbladder wall or a mass within the gallbladder. Generally, it appears as low signal on T1-weighted images and high signal on T2-weighted images. After enhancement, the lesion shows obvious enhancement. If the lesion is large, necrosis may occur internally. Since the gallbladder is close to the liver, if abnormal signals are found in the liver, intrahepatic metastasis should be considered, which further confirms the possibility of gallbladder cancer. Additionally, gallbladder cancer can also invade the nearby bile ducts, causing dilation of the bile ducts, as well as local or distant lymph node metastasis.

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Written by Shen Jiang Chao
Radiology
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Can gallbladder cancer be detected by ultrasound?

Gallbladder cancer can also be detected by ultrasound, which is the preferred imaging method for diagnosing hepatobiliary diseases. Ultrasound can detect space-occupying lesions in hepatobiliary diseases early on. It is sensitive enough to detect lesions as small as one centimeter, or even a few millimeters. In the case of space-occupying lesions of the gallbladder, particularly gallbladder cancer, there are no particularly obvious signals on ultrasound. Ultrasound of the gallbladder is merely used as a screening tool, not as a definitive diagnostic method. If gallbladder cancer is suspected, further investigations such as MRI or enhanced CT are generally required, but the final diagnosis still relies on pathology.