The main manifestations of gallbladder cancer on MRI

Written by Shen Jiang Chao
Radiology
Updated on September 14, 2024
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Gallbladder cancer is more common in females and is generally believed to be associated with chronic stimulation from chronic cholecystitis and gallstones. On MRI, gallbladder cancer can be categorized into several types based on case classification and growth patterns: first, the infiltrative type; second, the nodular type; third, the mass-forming type; and fourth, the obstructive type. Regardless of the pathological type of gallbladder cancer, the tumor tissue appears as a heterogeneous low signal on T1 and a heterogeneous high signal on T2. After enhancement, the tumor shows heterogeneous enhancement. If there is invasion into the liver, the boundary with liver tissue is unclear. MRI has significant advantages in assessing invasion of adjacent organs and metastasis, and can provide great value for surgery or treatment planning.

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Written by Liu Wu Cai
Hepatobiliary Surgery
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Can people with gallbladder cancer eat sea cucumber?

Patients with gallbladder cancer can eat sea cucumber. For patients with gallbladder cancer, there may be a decrease in resistance, especially a tendency for weight loss, and even the development of cachexia and hypoalbuminemia. Therefore, patients should pay attention to their diet and supplement it with foods high in protein to meet the body's needs for albumin and improve the patient's resistance. Furthermore, the diet of patients with gallbladder cancer should also avoid spicy and irritating foods to reduce inflammatory irritation. They should eat more fresh vegetables and fruits to better control the progression of the disease. For gallbladder cancer, treatment should ideally involve early surgical removal to achieve better prognosis.

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Written by Liu Wu Cai
Hepatobiliary Surgery
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Can gallbladder cancer be detected through blood tests?

Blood tests generally cannot detect gallbladder cancer because there are no specific markers in the blood tests for gallbladder cancer. Although some tumor markers may be significantly elevated, they are not specific. Therefore, diagnosis of gallbladder cancer can be refined through abdominal CT, color ultrasound, and if necessary, puncture tissue for pathological examination to confirm the nature. Once diagnosed with gallbladder cancer, surgery should be performed as soon as possible because gallbladder cancer is a highly malignant, rapidly developing, and poor prognosis malignancy. It is important to pay attention to it and handle it promptly to improve the prognosis and potentially extend the patient’s life.

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Written by Shen Jiang Chao
Radiology
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Gallbladder cancer ultrasonographic appearance

The appearance of gallbladder cancer on color ultrasound depends on the morphology of the cancer, which is mainly divided into five types: small nodular, thick-wall, fragmented, calculous, and mixed type. The small nodular type mainly features a polypoid elevation with a wide base, about 1-1.2 cm in size, and has isoechoic characteristics. The fragmented type is characterized by a wider base and irregular borders, presenting as hypoechoic or isoechoic masses. The calculous type shows an enlarged gallbladder, possibly containing hypoechoic and uneven solid masses that may fill the entire gallbladder. The thick-wall type primarily involves localized or diffuse thickening of the wall. The mixed type is a combination of papillary fragmented type and thick-wall type presence.

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Written by Liu Wu Cai
Hepatobiliary Surgery
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Is gallbladder cancer prone to spreading?

Gallbladder cancer is a type of cancer that is prone to spreading and is of a higher malignancy level. It is difficult to detect in the early stages. Patients with gallbladder cancer may initially present with subtle right upper abdominal pain, which is often overlooked. Therefore, once diagnosed with gallbladder cancer, it generally has reached the mid to late stages. At this time, the patient's pain becomes significant, which is the primary reason for seeking medical attention. Gallbladder cancer progresses rapidly and is prone to metastasize to other locations, such as the liver, leading to liver dysfunction, jaundice, ascites, hypoalbuminemia, and more. Additionally, for gallbladder cancer, the treatment strategy emphasizes early surgical removal to achieve better therapeutic outcomes.

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Written by Liu Wu Cai
Hepatobiliary Surgery
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Will CA199 also be high with gallbladder cancer?

Gallbladder cancer CA199 levels are likely to be elevated. In the case of gallbladder cancer, it is a common malignant tumor of the digestive system. When tumor markers are evaluated, an increase in CA199 can be observed. For patients with gallbladder cancer, it is advisable to undergo surgical removal as early as possible to improve prognosis. Generally, early-stage gallbladder cancer patients do not show specific symptoms, and some may only experience upper abdominal bloating and discomfort, which is often overlooked. Therefore, once diagnosed with gallbladder cancer, it is usually at a mid-to-late stage. At this point, treatment can only be symptomatic and not curative, and the treatment outcome is relatively poor. However, active management is still necessary to prevent the worsening of the condition.