Can gallbladder cancer be detected by cancer embryonic antigen test?

Written by Liu Wu Cai

Hepatobiliary Surgery

Updated on December 16, 2024

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The use of cancer embryo antigen in patients with gallbladder cancer has certain reference value, but it is not absolute.

Patients with gallbladder cancer typically show a significant increase in embryonic antigen. Gallbladder cancer is difficult to diagnose early as it generally does not show specific symptoms. Some patients may experience mild discomfort in the upper right abdomen, but this is often overlooked or misdiagnosed as other diseases, such as chronic gastritis.

Therefore, once diagnosed with gallbladder cancer, it is usually already at a middle to late stage. Although the cancer embryo antigen in tumor marker tests of gallbladder cancer patients can be elevated, this is not absolute. Therefore, when discomfort in the upper right abdomen occurs, further comprehensive examinations like color ultrasound, CT, and other related tests are necessary to differentiate it.

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Written by Liu Wu Cai

Hepatobiliary Surgery

1min 2sec

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What foods to eat for late-stage gallbladder cancer?

Patients with advanced liver cancer will experience metastasis to other parts of the body, presenting corresponding clinical symptoms that affect the quality of life. Furthermore, patients with advanced liver cancer often exhibit significant weight loss and cachexia, commonly accompanied by hypoalbuminemia. Therefore, for patients with advanced gallbladder cancer, it is advisable to include a diet rich in high-protein foods, which can help replenish the proteins needed by the body, such as albumin, and improve the patient's immunity. It is beneficial to eat fresh vegetables, fruits, as well as lean meats, eggs, and fish, to address these symptoms appropriately. At the same time, for patients with advanced gallbladder cancer, it is important to avoid spicy and irritating foods, as well as foods that are difficult to digest, because these can increase the burden on the gallbladder, exacerbating the condition and impeding treatment. Hence, this should be given careful consideration.

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Written by Liu Wu Cai

Hepatobiliary Surgery

47sec

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Can gallbladder cancer be detected through blood tests?

Blood tests generally cannot detect gallbladder cancer because there are no specific markers in the blood tests for gallbladder cancer. Although some tumor markers may be significantly elevated, they are not specific. Therefore, diagnosis of gallbladder cancer can be refined through abdominal CT, color ultrasound, and if necessary, puncture tissue for pathological examination to confirm the nature. Once diagnosed with gallbladder cancer, surgery should be performed as soon as possible because gallbladder cancer is a highly malignant, rapidly developing, and poor prognosis malignancy. It is important to pay attention to it and handle it promptly to improve the prognosis and potentially extend the patient’s life.

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Written by Shen Jiang Chao

Radiology

53sec

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Gallbladder cancer ultrasonographic appearance

The appearance of gallbladder cancer on color ultrasound depends on the morphology of the cancer, which is mainly divided into five types: small nodular, thick-wall, fragmented, calculous, and mixed type. The small nodular type mainly features a polypoid elevation with a wide base, about 1-1.2 cm in size, and has isoechoic characteristics. The fragmented type is characterized by a wider base and irregular borders, presenting as hypoechoic or isoechoic masses. The calculous type shows an enlarged gallbladder, possibly containing hypoechoic and uneven solid masses that may fill the entire gallbladder. The thick-wall type primarily involves localized or diffuse thickening of the wall. The mixed type is a combination of papillary fragmented type and thick-wall type presence.

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Written by Liu Wu Cai

Hepatobiliary Surgery

56sec

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Is jaundice a sign of advanced gallbladder cancer?

If a patient with gallbladder cancer exhibits jaundice, it does not necessarily mean the cancer is in its late stages. As the cancer grows, it may compress the bile duct, leading to obstructive jaundice. This can result in lighter-colored stools, darker urine, and yellowing of the skin and mucous membranes, and even cause itchy skin. Therefore, it is not necessarily indicative of advanced gallbladder cancer. Of course, if a patient with late-stage gallbladder cancer experiences liver metastasis, this might also manifest as yellowing of the skin and mucous membranes throughout the body. At this point, it is necessary to carry out thorough examinations, common tests including abdominal CT scans and ultrasounds, which can better assess the condition. If metastasis is present, even systemic chemotherapy might be required to achieve a better treatment outcome.

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Written by Liu Wu Cai

Hepatobiliary Surgery

54sec

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Will CA199 also be high with gallbladder cancer?

Gallbladder cancer CA199 levels are likely to be elevated. In the case of gallbladder cancer, it is a common malignant tumor of the digestive system. When tumor markers are evaluated, an increase in CA199 can be observed. For patients with gallbladder cancer, it is advisable to undergo surgical removal as early as possible to improve prognosis. Generally, early-stage gallbladder cancer patients do not show specific symptoms, and some may only experience upper abdominal bloating and discomfort, which is often overlooked. Therefore, once diagnosed with gallbladder cancer, it is usually at a mid-to-late stage. At this point, treatment can only be symptomatic and not curative, and the treatment outcome is relatively poor. However, active management is still necessary to prevent the worsening of the condition.