If there is gallbladder cancer, we can detect it by conducting an ultrasound examination, checking the liver, gallbladder, pancreas, and spleen, or simply performing an upper abdominal ultrasound. This is because an ultrasound is typically the first choice for examining the hepato-biliary system. Why? Because it's the most convenient and quickest method. Other examinations such as CT scans or MRI often require a prior appointment, especially MRI, which may need booking days in advance. However, ultrasounds are usually done on the same day and the results are immediate, making it the preferred method for examining the liver and gallbladder. Moreover, ultrasound is quite sensitive for gallbladder cancer. It can reveal if the gallbladder wall is particularly thickened, either locally or extensively, which often suggests the presence of gallbladder cancer, or if there is a large mass of soft tissue in the area of the gallbladder fossa, which might also adhere to the surrounding liver, raising suspicions of gallbladder cancer. Additionally, if there are unusually large polyps, particularly those over 1cm or with a notably wide base, gallbladder cancer should also be considered.