Nasopharyngeal carcinoma clinical manifestations

Written by Deng Bang Yu
Otolaryngology
Updated on September 17, 2024
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Nasopharyngeal carcinoma is the most common malignant tumor in the nasopharyngeal area, and clinically, it is primarily squamous cell carcinoma. The incidence of nasopharyngeal carcinoma is particularly high in the southern regions of China, especially in Guangdong. Initially, nasopharyngeal carcinoma manifests locally as a tumorous mass in the nasopharyngeal area, often with ulceration on the surface. This can lead to the presence of blood in nasal mucus, known as bloody nasal discharge. As the disease progresses, there can be swelling of the cervical lymph nodes, primarily involving the upper deep cervical lymph nodes, with about 60% of patients experiencing this type of lymph node enlargement. As the tumor enlarges, it may block the nasal passage, leading to persistent nasal congestion. The tumor's pressure on the Eustachian tube can cause symptoms of secretory otitis media. Furthermore, damage to the skull base by the tumor can lead to severe headaches. As a malignant tumor, the cancer can cause systemic symptoms such as malnutrition and cachexia. In advanced stages, metastatic symptoms may appear, such as bone and liver metastases, affecting these vital organs.

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Causes of Nasopharyngeal Carcinoma

Nasopharyngeal carcinoma is a common malignant tumor in otolaryngology, ranking first in incidence among otolaryngological diseases. The main causes are often associated with the patient's long-term chronic inflammation in the nasal cavity, smoking, drinking, and other bad habits. For patients with nasal cancer, it is mainly about avoiding exposure to irritating gases and abstaining from smoking and drinking in daily life to prevent the occurrence of nasal cancer. Additionally, we can use electronic nasopharyngoscopy, electronic laryngoscopy, and blood system EB virus tests, among others, to exclude nasopharyngeal carcinoma. If local tumor proliferation is found in the pharyngeal recess or nasopharynx, biopsy forceps can be used to remove the patient's tumor for pathological examination and diagnosis.

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Can patients with nasopharyngeal carcinoma eat peaches?

Nasopharyngeal carcinoma is a relatively common type of malignant tumor in the head and neck area. Peaches can be eaten; they are a common type of fruit containing rich vitamins, and they have no direct side effects on the condition of nasopharyngeal carcinoma, nor do they affect the treatment efficacy. They also do not directly conflict with any medications or treatment plans related to nasopharyngeal carcinoma. Therefore, it is normal to consume peaches. For patients with nasopharyngeal carcinoma, it is advised that their diet should be high in protein and low in fat, with balanced and reasonable nutrition to ensure adequate energy supply and enhanced immunity, which can help with the treatment of the condition.

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How is nasopharyngeal carcinoma diagnosed?

The examination of nasopharyngeal carcinoma is mainly divided into two major categories. The first category is imaging examinations, and the second category is pathological biopsy tests. Imaging examinations primarily involve performing a CT or MRI of the nasopharyngeal area to determine the scope of the cancerous changes in the nasopharynx, which is quite helpful for clinical staging and typing. It also plays a role in designing targeted therapy for subsequent radiation treatment. Pathological testing is an important means for diagnosing nasopharyngeal carcinoma. Generally, it requires a nasopharyngoscopy. If cancerous changes are suspected during the nasopharyngoscopy, a pathological biopsy can be taken simultaneously. After the biopsy, the specific differentiation degree and type of cancer can be determined. Then, in conjunction with the imaging examinations, a plan for radiotherapy and chemotherapy can be formulated.

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Written by Li Rui
Otolaryngology
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Early symptoms of nasopharyngeal carcinoma

The symptoms of nasal cancer can be numerous. In the early stages, symptoms might not be apparent because the area affected is relatively small, which can make the symptoms unclear. Possible symptoms include bloody nasal discharge and poor nasal airflow. Some patients might experience a foreign body sensation in the nasopharyngeal area. The most important thing, however, is to use diagnostic aids to make an assessment. This can include a nasopharyngoscopy, an enhanced CT of the nasopharynx, or an enhanced MRI to preliminarily determine the presence of a tumor. If a tumor is suspected, it is possible to consider performing a biopsy and lab tests under endoscopy. Only after completing the biopsy and lab tests can it be confirmed whether it is nasopharyngeal cancer, and then further treatment plans can be considered.

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What tests are done for nasopharyngeal carcinoma?

The examination items for nasopharyngeal carcinoma are mainly divided into three types. The first type is imaging examinations, the second type is blood tests, and the third type is endoscopic pathological biopsy. Imaging examinations mainly involve CT or MRI of the nasopharynx and the whole body. If necessary, PET-CT may also be considered to clarify the extent of the condition and determine the presence of neck or distant metastases, which is helpful for diagnosis and adjuvant therapy. The second type involves blood tests, mainly including general biochemical blood tests and virus detection, which can assess the basic functional status of the body. The third type is the endoscopic pathological biopsy, which involves performing a pathological biopsy under nasal endoscopy, primarily to confirm the diagnosis and observe the extent of the lesion in the nasopharynx.