The contagious period of shingles is about two weeks, so it is advisable to isolate for two to three weeks. Shingles typically occurs in people with weakened immune systems and is mainly caused by the varicella-zoster virus. The primary symptoms are red blister clusters on the skin that follow nerve pathways, accompanied by significant pain. Treatment primarily focuses on antiviral medication, nourishing the nerves, and relieving pain. Generally, within two to three weeks, the rash can crust over and shed, at which point it is no longer contagious, and isolation is no longer necessary.