How to deal with abdominal pain from allergic purpura?

Written by Li Jing
Rheumatology
Updated on September 13, 2024
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The most common clinical manifestations of allergic purpura are bleeding spots on the lower limbs, hematuria, melena, and joint pain. The presence of melena or bloody stools accompanied by abdominal pain often indicates bleeding from the intestinal mucosa. It is recommended to complete a mesenteric vascular color Doppler ultrasound as soon as possible to identify the bleeding sites. At this time, fasting is absolutely necessary, meaning no food or water should be consumed, as this can exacerbate abdominal pain and bleeding. Fasting should continue until the melena and pain are alleviated. If symptoms continue to worsen, surgery may be necessary to prevent intestinal perforation and the onset of acute peritonitis.

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Can allergic purpura be cured completely?

Allergic purpura is a type of vasculitis that recurs symptomatically, but most cases can be cured with systematic and standardized medication. This disease has complex classifications including skin type, gastrointestinal type, joint type, and renal type. The simple types generally have milder symptoms and are easier to cure; however, complex damages often exhibit a clinical characteristic of being difficult to cure. It is important to rest, control physical activity, and follow a cautious and reasonable diet, avoiding cold foods and seafood. Treatment involves anti-inflammatory measures, improving the permeability of peripheral blood vessels, and supporting immune regulation.

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Precautions for Allergic Purpura

Allergic purpura is a common allergic disorder, also known as vasculitis, and occurs more frequently in adolescent males. Adults can also be affected, but it is less common, and the majority of cases are due to infections, such as bacterial, viral, or parasitic infections. Food or drug allergies are also part of the causes of allergic purpura. For adolescents who develop allergic purpura, infections should be considered first, followed by allergies. It's important to maintain a light diet, drink plenty of water, wear a mask when going out to prevent upper respiratory infections, and control the intake of high-protein foods such as fish, shrimp, eggs, milk, and lean meat. As for fruits, including mangoes, some people can be triggered to have allergic purpura, especially fruits they have not been exposed to before; it's best to minimize contact with unfamiliar fruits to avoid inducing an allergic purpura attack.

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Written by Yang Ya Meng
Rheumatology
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What medicine is taken for allergic purpura?

The medication for allergic purpura should be determined based on the severity of the patient's condition. If the patient only shows symptoms like rashes, the focus should be on reducing the rashes, and medications such as compound glycyrrhizin and desloratadine can be used for their anti-allergic effects. If the main clinical manifestation of allergic purpura is joint pain, some non-steroidal pain relief medications can be added for pain relief. However, if the patient primarily exhibits involvement of internal organs, such as gastrointestinal involvement in allergic purpura starting with abdominal pain, or kidney damage marked by significant proteinuria, then corticosteroids and immunosuppressants should be considered for treatment. (Please use medications under the guidance of a doctor).

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Rheumatology
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Precursors of recurrent allergic purpura

The precursors of a relapse of allergic purpura typically occur in patients after exposure to cold, strenuous exercise, or allergens, manifesting as purpuric rash on the skin. Additionally, some patients may experience gastrointestinal reactions such as nausea, vomiting, abdominal pain, and diarrhea. More severe cases can present with symptoms of allergic purpura and purpura nephritis, primarily characterized by edema and significant proteinuria indicated in routine urine tests. If patients experience the aforementioned symptoms, it is crucial to be vigilant about the possibility of a relapse of allergic purpura and to seek medical attention promptly to prevent further progression of the disease.

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Can allergic purpura be inherited?

Allergic purpura is mostly caused by exposure to infections, medications, or foods, leading to skin and mucous membrane ecchymoses, which are essentially petechiae and a manifestation of vasculitis. It falls under autoimmune diseases, not genetic diseases, and thus is not contagious. Bacterial, viral, mycoplasmal, or parasitic infections are the most common causes. Secondarily, medications and foods can also trigger allergic purpura, such as high-protein foods like seafood and milk. Therefore, if there are symptoms like ecchymoses on the lower extremities accompanied by joint pain, or signs of blood in the stool or black stool, it is necessary to complete routine blood tests, erythrocyte sedimentation rate, and autoimmune antibody tests to rule out other autoimmune diseases. During the acute phase, it is advisable to rest in bed, eat a light diet, avoid infection, and use corticosteroids for anti-allergy treatment if necessary.