Stage IB endometrial cancer treatment

Written by Xu Xiao Ming
Obstetrics and Gynecology
Updated on September 15, 2024
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Endometrial carcinoma Stage IB refers to tumors localized to the body of the uterus, where tumor infiltration is less than half of the myometrium. Surgical treatment is feasible for this stage and involves a slightly extensive total hysterectomy coupled with bilateral adnexectomy. During the surgery, a frozen section pathology test should be conducted. If the pathology report from the frozen section indicates special types of endometrial-like cancer, including papillary serous adenocarcinoma, clear cell carcinoma, squamous cell carcinoma, carcinosarcoma, and undifferentiated carcinoma, additional procedures are required. Moreover, if enlarged para-aortic or common iliac lymph nodes are palpated during the surgery, lymphadenectomy of the pelvic and para-aortic lymph nodes should be performed.

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Written by Du Rui Xia
Obstetrics
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Late-stage symptoms of endometrial cancer

Endometrial cancer is a common malignant tumor in the female reproductive system. In advanced stages, patients often experience irregular vaginal bleeding. In addition, there may be bloody discharge from the vagina. If an infection is present or there are signs of necrosis due to the cancer, there may also be purulent discharge or other foul odors. Additionally, there are more apparent symptoms such as pain, abdominal masses, and in late stages, the cancer may invade blood vessels, causing swelling in the lower limbs, or spread to nearby organs, such as the ureters, leading to renal damage. Over time, this can also lead to cachexia, fever, and other signs of systemic failure.

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Written by Du Rui Xia
Obstetrics
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How to stop bleeding from endometrial cancer.

In cases of bleeding in endometrial cancer, treatment generally relies heavily on a large amount of progesterone, along with some hemostatic drugs. Additionally, it is advised that patients with endometrial cancer undergo prompt surgical removal. Treatment should also be combined with radiotherapy and chemotherapy based on biopsy results, to provide a comprehensive approach. Using medication to stop bleeding only achieves a palliative effect and cannot completely cure the disease. Endometrial cancer significantly impacts women's health. Therefore, the condition should not be allowed to progress, and surgery should be performed as soon as it is discovered. (The use of medications should be conducted under the guidance of a professional doctor.)

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Written by Xu Xiao Ming
Obstetrics and Gynecology
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How is endometrial cancer diagnosed?

If it concerns endometrial cancer, postmenopausal vaginal bleeding and menstrual disorders during the menopausal transition should prompt an exclusion of endometrial cancer. The most common and valuable method for diagnosing endometrial cancer is through pathological examination results, especially via fractional curettage. The advantage of fractional curettage is that it can differentiate between endometrial cancer and cervical adenocarcinoma, and it can clarify whether the cervical canal is involved, providing a basis for formulating treatment plans. In addition, endometrial cancer can also be assessed using a B-mode ultrasound, but this is only used to provide reference values for clinical diagnosis and management. Another method is hysteroscopy, which allows direct observation of the uterine cavity and cervical canal for any lesions, and tissue can also be collected for biopsy, which is also a very good method.

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Written by Tang Mei Xiang
Obstetrics and Gynecology
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How is endometrial cancer diagnosed?

Endometrial cancer often manifests as vaginal bleeding after menopause, and in women who have not experienced menopause, it often presents as menstrual irregularities. The diagnostic methods for endometrial cancer include the following: 1. Fractional curettage is the most important method for diagnosing endometrial cancer. First, scrape the cervical canal, then sequentially scrape the endometrial tissue from each part of the uterine body, label the specimens separately, and send them for pathological examination together. 2. Cytological examination is a method for screening for endometrial cancer. A specially made uterine cavity suction tube or brush is inserted into the uterine cavity to collect secretions for cytological culture. 3. Hysteroscopic examination allows direct observation of the growth of endometrial lesions and can also obtain live tissue for pathological examination. It involves pelvic ultrasound examination to understand the size of the lesion, surrounding infiltration, etc. 5. Other methods, such as lymphangiography, CT, MRI, and serum CA125 testing.

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Written by Xu Xiao Ming
Obstetrics and Gynecology
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Does endometrial cancer require chemotherapy?

Whether chemotherapy is needed for endometrial cancer depends on its clinical stage. If it is advanced endometrial cancer, such as stage IV, chemotherapy is necessary for these patients. Recurrent endometrial cancer also requires chemotherapy. In the case of early-stage endometrial cancer, surgery can be used. The purpose of the surgery is to stage the pathology of the cancer to determine the extent of endometrial cancer infiltration. After the surgery, it will be assessed whether chemotherapy is needed. Therefore, whether chemotherapy is needed for endometrial cancer depends on the surgical staging. Some endometrial cancers may require not only chemotherapy but also radiotherapy treatment.