Is endometrial hyperplasia the same as cancer?

Written by Li Shun Hua
Obstetrics and Gynecology
Updated on September 05, 2024
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Endometrial hyperplasia is not cancer; it is caused by a prolonged absence of ovulation, which means there is no secretion of progesterone. This prevents the proliferative phase endometrium from transforming into the secretory phase, leading to hyperplasia. If the hyperplasia persists over an extended period, it may lead to precancerous changes in the endometrium, and in severe cases, it can cause endometrial cancer. Therefore, it is essential to treat endometrial hyperplasia with progesterone, which can transform the endometrium and allow it to shed completely, altering its condition and restoring it to normal. As long as there is ovulation, there is the production of progesterone, so promoting ovulation is crucial.

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How is endometrial cancer staged?

Endometrial cancer is a common gynecological malignancy in women. Based on surgical and pathological results, endometrial cancer can be divided into four stages. Stage I is the mildest form of endometrial cancer, where the cancer is confined only within the endometrium and does not extend beyond the uterine serosa. Generally, stage 1a is when the cancer is less than half the width of the muscle, while stage 1b is when the cancer infiltrates more than half the width of the muscle. Stage II means the cancer has locally spread but only involves the cervix, without causing cervical stromal infiltration. Stage III involves local spread to the serosa and lymph nodes. Stage IV involves distant metastasis, such as to the liver and bones.

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Can endometrial cancer patients become pregnant?

After the occurrence of endometrial cancer, it is not possible to become pregnant. This is because, after pregnancy, a woman's immunity decreases, and her resistance to illness declines. This will affect the woman's health and may exacerbate the condition of endometrial cancer. Additionally, women with endometrial cancer, even if they become pregnant, may experience miscarriages as the embryo cannot develop normally, and even many harmful symptoms might occur, affecting the woman's health. Therefore, women with endometrial cancer should take contraceptive measures to prevent unintended pregnancies.

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Stage IB endometrial cancer treatment

Endometrial carcinoma Stage IB refers to tumors localized to the body of the uterus, where tumor infiltration is less than half of the myometrium. Surgical treatment is feasible for this stage and involves a slightly extensive total hysterectomy coupled with bilateral adnexectomy. During the surgery, a frozen section pathology test should be conducted. If the pathology report from the frozen section indicates special types of endometrial-like cancer, including papillary serous adenocarcinoma, clear cell carcinoma, squamous cell carcinoma, carcinosarcoma, and undifferentiated carcinoma, additional procedures are required. Moreover, if enlarged para-aortic or common iliac lymph nodes are palpated during the surgery, lymphadenectomy of the pelvic and para-aortic lymph nodes should be performed.

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Written by Li Shun Hua
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Is endometrial hyperplasia cancer?

Endometrial hyperplasia is not cancer; the normal endometrial lining is in a proliferative state. Endometrial hyperplasia occurs due to a lack of secretion of progesterone. If it continues to develop, it can progress to atypical endometrial hyperplasia, which is a precancerous condition of the endometrium. If not treated in time, it could develop into endometrial cancer. Thus, active treatment of endometrial hyperplasia is necessary. Large doses of progesterone can be used to promote the transformation of the endometrial lining. Once the endometrium transforms into the secretory phase, it indicates that the endometrial hyperplasia has been effectively treated and can prevent the progression to endometrial cancer.

doctor image
home-news-image
Written by Li Shun Hua
Obstetrics and Gynecology
55sec home-news-image

Is endometrial hyperplasia cancer?

Endometrial hyperplasia is not the same as endometrial cancer; it can be treated promptly. Endometrial cancer develops from ongoing endometrial hyperplasia, which can progress into atypical hyperplasia, a precancerous condition of the endometrium. Further development can lead to endometrial cancer. Therefore, it is crucial to treat endometrial hyperplasia actively to prevent its progression to endometrial cancer. Endometrial hyperplasia results from a lack of progesterone influence, causing the endometrium to remain in a proliferative state rather than transitioning to the secretory phase. With the influence of progesterone, the endometrium would not undergo hyperplasia; therefore, treating endometrial hyperplasia with progesterone is advisable.