Is endometrial hyperplasia the same as cancer?

Written by Li Shun Hua
Obstetrics and Gynecology
Updated on September 05, 2024
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Endometrial hyperplasia is not cancer; it is caused by a prolonged absence of ovulation, which means there is no secretion of progesterone. This prevents the proliferative phase endometrium from transforming into the secretory phase, leading to hyperplasia. If the hyperplasia persists over an extended period, it may lead to precancerous changes in the endometrium, and in severe cases, it can cause endometrial cancer. Therefore, it is essential to treat endometrial hyperplasia with progesterone, which can transform the endometrium and allow it to shed completely, altering its condition and restoring it to normal. As long as there is ovulation, there is the production of progesterone, so promoting ovulation is crucial.

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Written by Shen Li Wen
Obstetrics and Gynecology
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Is surgery necessary for endometrial cancer?

When a woman suffers from endometrial cancer, the primary treatment method is surgery, but there are some special circumstances. For example, if the lesion in the woman is relatively minor, it is atypical hyperplasia, which is a precancerous condition, or it is in the late stage of the disease, or in cases of recurrent endometrial cancer. At this time, treatment can be administered using progestogen drugs, applying high-dose long-term oral intake of effective progestogens, which can suppress the cancerous transformation of the endometrial lining and inhibit the further proliferation of cancer cells. Generally, it involves continuous oral administration for 12 weeks, which is three months, followed by a diagnostic curettage to evaluate the therapeutic effects of the drug. In addition, radiation therapy can also be considered.

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Written by Li Shun Hua
Obstetrics and Gynecology
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Is endometrial hyperplasia cancer?

Endometrial hyperplasia is not the same as endometrial cancer; it can be treated promptly. Endometrial cancer develops from ongoing endometrial hyperplasia, which can progress into atypical hyperplasia, a precancerous condition of the endometrium. Further development can lead to endometrial cancer. Therefore, it is crucial to treat endometrial hyperplasia actively to prevent its progression to endometrial cancer. Endometrial hyperplasia results from a lack of progesterone influence, causing the endometrium to remain in a proliferative state rather than transitioning to the secretory phase. With the influence of progesterone, the endometrium would not undergo hyperplasia; therefore, treating endometrial hyperplasia with progesterone is advisable.

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Written by Tang Mei Xiang
Obstetrics and Gynecology
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How is endometrial cancer diagnosed?

Endometrial cancer often manifests as vaginal bleeding after menopause, and in women who have not experienced menopause, it often presents as menstrual irregularities. The diagnostic methods for endometrial cancer include the following: 1. Fractional curettage is the most important method for diagnosing endometrial cancer. First, scrape the cervical canal, then sequentially scrape the endometrial tissue from each part of the uterine body, label the specimens separately, and send them for pathological examination together. 2. Cytological examination is a method for screening for endometrial cancer. A specially made uterine cavity suction tube or brush is inserted into the uterine cavity to collect secretions for cytological culture. 3. Hysteroscopic examination allows direct observation of the growth of endometrial lesions and can also obtain live tissue for pathological examination. It involves pelvic ultrasound examination to understand the size of the lesion, surrounding infiltration, etc. 5. Other methods, such as lymphangiography, CT, MRI, and serum CA125 testing.

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Written by Li Lin
Obstetrics and Gynecology
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Stage IA endometrial cancer

Endometrial cancer is a group of epithelial malignant tumors that occur in the endometrium. Clinically, the surgical pathology staging revised by the World Health Organization in 2000 is mainly used, based on the severity of the lesion after surgery. Endometrial cancer can be divided into four stages, where, depending on the size and severity of the lesion, it can further be classified into sub-stages a, b, and c. Stage IA refers to cancer limited to the endometrium and is the earliest stage of endometrial cancer. Stage IA endometrial cancer can be completely cured with surgical treatment.

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Written by Du Rui Xia
Obstetrics
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Can endometrial cancer patients become pregnant?

After the occurrence of endometrial cancer, it is not possible to become pregnant. This is because, after pregnancy, a woman's immunity decreases, and her resistance to illness declines. This will affect the woman's health and may exacerbate the condition of endometrial cancer. Additionally, women with endometrial cancer, even if they become pregnant, may experience miscarriages as the embryo cannot develop normally, and even many harmful symptoms might occur, affecting the woman's health. Therefore, women with endometrial cancer should take contraceptive measures to prevent unintended pregnancies.