Is endometrial hyperplasia cancer?

Written by Li Shun Hua

Obstetrics and Gynecology

Updated on September 22, 2024

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Endometrial hyperplasia is not the same as endometrial cancer; it can be treated promptly. Endometrial cancer develops from ongoing endometrial hyperplasia, which can progress into atypical hyperplasia, a precancerous condition of the endometrium. Further development can lead to endometrial cancer. Therefore, it is crucial to treat endometrial hyperplasia actively to prevent its progression to endometrial cancer. Endometrial hyperplasia results from a lack of progesterone influence, causing the endometrium to remain in a proliferative state rather than transitioning to the secretory phase. With the influence of progesterone, the endometrium would not undergo hyperplasia; therefore, treating endometrial hyperplasia with progesterone is advisable.

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Obstetrics and Gynecology

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Endometrial cancer leukorrhea symptoms

The main manifestation of endometrial discharge is an increase in the amount of discharge, which can be watery or bloody. Sometimes, it can also appear as pus-blood-like discharge. Another main symptom of endometrial cancer is irregular vaginal bleeding. During an ultrasound, uneven echoes can be seen within the uterine cavity. The patient may also experience pain in the lower abdomen and increased menstrual flow. Therefore, if there are abnormalities in menstruation or unusual vaginal discharge, it is necessary to promptly go to the hospital for an ultrasound and gynecological examinations, and receive treatment based on the results of these tests.

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Obstetrics and Gynecology

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Causes of Endometrial Cancer

Patients with endometrial cancer generally have factors such as hypertension, diabetes, and obesity that induce the condition. They are more prone to developing endometrial cancer. Furthermore, endometrial cancer is divided into hormone-dependent and non-hormone-dependent types. Hormone-dependent endometrial cancer occurs when there is an excess of estrogen produced in the body without sufficient counteraction by progesterone, leading to excessive growth and proliferation of the endometrial lining. When this growth becomes uncontrolled, it can lead to cancer. Non-hormone-dependent endometrial cancer is not caused by hormonal factors and its development is more complex. Additionally, the pathology type of non-hormone-dependent endometrial cancer is also quite unique.

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Written by Yan Chun

Oncology

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What are the symptoms of endometrial cancer?

Patients with endometrial cancer mainly experience symptoms in three areas: First, obvious symptoms caused by local tumors in the uterus, such as irregular vaginal bleeding, changes in the menstrual cycle, a sense of fullness and dull pain in the lower abdomen and pelvic area, along with significant discomfort and pain. Second, clinical symptoms caused by metastatic lesions. Endometrial cancer can spread through three pathways, which after dissemination can cause a variety of symptoms, such as abdominal pain, bloating, constipation, headache, vomiting, movement disorders, chest tightness, coughing, wheezing, and difficulty breathing. Some patients may also experience bone pain. Third, systemic symptoms, which are typically seen in advanced stages of endometrial cancer and commonly include cachexia, fever, and others.

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Written by Li Shun Hua

Obstetrics and Gynecology

50sec

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Is endometrial hyperplasia cancer?

Endometrial hyperplasia is not cancer; the normal endometrial lining is in a proliferative state. Endometrial hyperplasia occurs due to a lack of secretion of progesterone. If it continues to develop, it can progress to atypical endometrial hyperplasia, which is a precancerous condition of the endometrium. If not treated in time, it could develop into endometrial cancer. Thus, active treatment of endometrial hyperplasia is necessary. Large doses of progesterone can be used to promote the transformation of the endometrial lining. Once the endometrium transforms into the secretory phase, it indicates that the endometrial hyperplasia has been effectively treated and can prevent the progression to endometrial cancer.

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Written by Xu Xiao Ming

Obstetrics and Gynecology

57sec

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How is endometrial cancer diagnosed?

If it concerns endometrial cancer, postmenopausal vaginal bleeding and menstrual disorders during the menopausal transition should prompt an exclusion of endometrial cancer. The most common and valuable method for diagnosing endometrial cancer is through pathological examination results, especially via fractional curettage. The advantage of fractional curettage is that it can differentiate between endometrial cancer and cervical adenocarcinoma, and it can clarify whether the cervical canal is involved, providing a basis for formulating treatment plans. In addition, endometrial cancer can also be assessed using a B-mode ultrasound, but this is only used to provide reference values for clinical diagnosis and management. Another method is hysteroscopy, which allows direct observation of the uterine cavity and cervical canal for any lesions, and tissue can also be collected for biopsy, which is also a very good method.