How long does rabies usually take to manifest?

Written by Xiong Hong Hai
Infectious Disease
Updated on May 14, 2025
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Rabies generally has a variable incubation period. The question actually refers to the incubation period of rabies. The duration of this period can vary widely; the shortest is about five days before onset of the disease, while the longest can reach up to eight years. The average incubation period is two to three months, with cases exceeding one year accounting for 2%-3% of instances. The length of the incubation period is related to factors such as the virulence of the virus, and the nerve distribution at the site of entry. The greater the amount of the virus, the stronger its virulence, and the richer the nerve supply at the site of entry, especially if it is closer to the central nervous system, the shorter the incubation period will be.

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Written by Han Jian Hua
Infectious Disease
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Rabies symptoms

Rabies is mainly characterized by hydrophobia, fear of wind, pharyngeal muscle spasms, progressive paralysis, etc. It is divided into: the prodromal phase, the excitative phase, and the paralytic phase, with varying symptoms in each phase.

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Infectious Disease
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Symptoms of rabies

After the onset of rabies, obvious clinical symptoms appear, including panic, irritability, and a range of neurological symptoms such as fear of wind, water, bright lights, and noise sensitivity. There can also be hyperextension, restlessness, hallucinations, and ultimately death due to coma. Once rabies begins to manifest, most patients die within 3-5 days, with very few surviving beyond a week. Rabies is a fatal disease, with a 100% mortality rate once infected, and there are no effective treatments available.

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Written by Xiong Hong Hai
Infectious Disease
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Does rabies cause diarrhea?

If rabies occurs, there may be symptoms like diarrhea and severe panic. A distinct fear and restlessness toward water, light, and wind are apparent. During the peak of rabies, a person will be in a state of significant agitation and extreme pain. Rabies is a deadly disease with a 100% mortality rate upon onset of symptoms. Currently, there are no treatment methods or strategies, so it is crucial to focus on the prevention of rabies.

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Infectious Disease
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Can rabies be treated?

Rabies, once contracted, is incurable and leads to a 100% fatality rate. The reason rabies is incurable primarily stems from the rabies virus invading the human body and proliferating extensively within the brain's nerves. This leads to the destruction of brain tissues and the exhaustion of brain functions, making it impossible to treat. Therefore, prevention of rabies is crucial. If there is exposure to the rabies virus, it is necessary to administer the rabies vaccine, and in some cases, it may also be necessary to administer rabies immunoglobulin concurrently.

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Written by Xiong Hong Hai
Infectious Disease
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Rabies transmission routes

Rabies is an extremely deadly disease, with a 100% fatality rate once infected, so prevention is crucial. According to clinical and laboratory research, the majority of cases result from bites by rabid dogs who were not vaccinated against rabies. Additionally, there are cases resulting from bites or scratches by cats who were not vaccinated. In places like the United States and Europe, bat bites are relatively common. In rabies cases involving dogs and cats, their saliva contains a high concentration of the virus, making infection likely if one comes into contact with it. Proper prevention is essential.