After the onset of rabies, obvious clinical symptoms appear, including panic, irritability, and a range of neurological symptoms such as fear of wind, water, bright lights, and noise sensitivity. There can also be hyperextension, restlessness, hallucinations, and ultimately death due to coma. Once rabies begins to manifest, most patients die within 3-5 days, with very few surviving beyond a week. Rabies is a fatal disease, with a 100% mortality rate once infected, and there are no effective treatments available.