How is rheumatoid arthritis treated?

Written by Yang Ya Meng
Rheumatology
Updated on September 27, 2024
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The treatment methods for rheumatoid arthritis mainly fall into three categories: The first category is anti-inflammatory analgesics, which include non-steroidal analgesic drugs such as slow-release diclofenac sodium. For patients with especially high inflammatory indicators, low-dose corticosteroids may also be considered. The second category of drugs includes slow-acting drugs commonly used in the treatment of rheumatoid arthritis, such as methotrexate and leflunomide, which are immunosuppressants. If the patient does not respond well to non-steroidal analgesic drugs or immunosuppressants, biological agents can be considered as a treatment option. Common biological agents include tumor necrosis factor antagonists. (Specific medications should be taken under the guidance of a physician.)

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Can people with rheumatoid arthritis donate blood?

Rheumatoid arthritis is a chronic systemic autoimmune disease characterized by symmetrical polyarthritis. It belongs to auto-immune diseases and is not an infectious disease; the cause of which is currently unclear. There is also considerable individual variation in its clinical manifestations. Because it is an autoimmune disease, it cannot be cured. This relates to whether or not one can donate blood: firstly, blood donors must not have any infectious diseases. Secondly, since this disease cannot be cured and patients often need to take regular doses of medications such as methotrexate, leflunomide, and sulfasalazine, there will be a certain concentration of these drugs in the body. If the condition allows and there are no infectious diseases, blood donation may be appropriately considered.

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Written by Li Jing
Rheumatology
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Differential diagnosis of rheumatoid arthritis

Rheumatoid arthritis is mostly related to streptococcal infections and needs to be differentiated from internal rheumatoid arthritis, ankylosing spondylitis, and other joint pains caused by autoimmune diseases. The main characteristic of rheumatoid arthritis is symmetrical pain in the joints of both hands, usually affecting multiple joints and accompanied by morning stiffness, and even systemic symptoms such as mild fever. The main features of ankylosing spondylitis are stiffness in the neck or pain in the lower back, with pain worsening after rest and alleviating after activity. Diagnosis requires a combination of CT of the sacroiliac joints and tests such as HLA-B27. Joint pain caused by other autoimmune diseases, such as systemic lupus erythematosus, often presents clinically with facial rashes, accompanied by hair loss, recurrent oral ulcers, and even Raynaud's phenomenon and mild fever. Diagnosis requires comprehensive tests including complete blood count, erythrocyte sedimentation rate, autoimmune antibodies, abnormal immunoglobulins, etc., based on the corresponding clinical manifestations and tests, to provide differential diagnosis.

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Written by Yang Ya Meng
Rheumatology
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Can rheumatoid arthritis be cured?

Rheumatoid arthritis is difficult to completely cure without medication, as it is a chronic inflammatory disease of the immune system that requires lifelong medication. The main treatment plans include the following three categories: The first category is anti-inflammatory and analgesic, which includes non-steroidal analgesics and low-dose corticosteroids. The second category, which is also the most important treatment, involves the use of immunosuppressants. Commonly used immunosuppressants include methotrexate and leflunomide. If the patient does not respond well to anti-inflammatory analgesics and immunosuppressants, treatment with biological agents may also be considered. (Medications should be used under the guidance of a doctor.)

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Written by Li Jing
Rheumatology
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Symptoms and treatment methods of rheumatoid arthritis

Rheumatic arthritis is mostly related to streptococcal infections. Additionally, respiratory viruses and mycoplasma infections can also cause joint pain. Once joint pain occurs, especially if it is asymmetrical, one should consider these infection-related factors, thus necessitating comprehensive tests including anti-streptolysin O, erythrocyte sedimentation rate, and respiratory virus tests. Whether to treat rheumatic arthritis depends on symptoms like fever and joint pain. Should there be fever and joint pain, proper medication is required, primarily the use of anti-inflammatory drugs, specifically non-steroidal ones. Treatment should be combined with long-term administration of penicillin to ensure a full course of therapy. If joint pain occurs, immobilization is essential, meaning bed rest is necessary until the joint pain eases. During this period, a light diet and adequate water intake are also recommended. (Please follow the guidance of a professional physician for medication use.)

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Written by Liu Li Ning
Rheumatology
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Rheumatoid arthritis is caused by what?

Rheumatic arthritis is a type of infectious arthritis caused by streptococcal infection and is one of the clinical manifestations of rheumatism. It primarily presents as migratory pain in large joints, most commonly affecting the large joints of the lower limbs, such as the knees, ankles, wrists, etc. Since rheumatic arthritis is related to streptococcal infection, treatment mainly involves the use of penicillin drugs, commonly long-acting penicillin, which requires strict adherence to the treatment course to completely cure the streptococcal infection. During the acute phase, joint pain often occurs, hence the common use of non-steroidal anti-inflammatory drugs, such as diclofenac sodium and etoricoxib, to alleviate symptoms of pain. During acute episodes, bed rest is necessary, with attention to joint immobilization. During the remission period, getting out of bed and exercising is encouraged to restore joint function and flexibility. (Please use medications under the guidance of a professional physician; do not self-medicate.)