The difference between osteoarthritis and rheumatoid arthritis.

Written by Wang Cheng Lin
Orthopedics
Updated on September 05, 2024
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Osteoarthritis and rheumatoid arthritis have distinct differences. Osteoarthritis commonly occurs in middle-aged and elderly women and is caused by the wear, degeneration, and rupture of joint cartilage, leading to swelling and pain due to friction during joint movement. On the other hand, rheumatoid arthritis is caused by bacterial infections leading to the proliferation of synovium in the joints, causing swelling and pain. Over time, this condition can damage the joint's cartilage and meniscus, severely affecting joint mobility. The treatments for these two diseases are different. Osteoarthritis can be alleviated through rest, oral medication, and physical therapy to ease local pain. If these methods are ineffective after more than six months, surgical treatment may be necessary, mainly total knee replacement. However, the treatment for rheumatoid arthritis primarily relies on medication to relieve local pain by removing rheumatism. (The use of medication should be under the guidance of a doctor.)

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Written by Yang Ya Meng
Rheumatology
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What medicine should be taken for rheumatoid arthritis?

Medications for rheumatoid arthritis firstly include some anti-inflammatory and analgesic drugs, commonly used are non-steroidal pain relievers such as Diclofenac Sodium Sustained Release Tablets and the like. The second, and most important, are what we call slow-acting drugs, which are often immunosuppressants, commonly used ones include Methotrexate, Leflunomide Tablets and the like. If the patient does not respond well to conventional oral medications, we can also use biologic treatments. Before using biologics, we need to strictly rule out hepatitis, tuberculosis, tumors, and some common infections. Commonly used biologics include tumor necrosis factor antagonists and similar drugs. (The use of medications should be conducted under the guidance of a professional doctor.)

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Written by Yang Ya Meng
Rheumatology
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Can people with rheumatoid arthritis drink alcohol?

Patients with rheumatoid arthritis can drink a small amount of alcohol, but long-term heavy drinking is not recommended. This is mainly because patients with rheumatoid arthritis need to take non-steroidal anti-inflammatory drugs (NSAIDs) for pain relief due to joint pain. The most significant side effect of these painkillers is their impact on the gastrointestinal tract. As alcohol is known to be harsh on the stomach, patients who take NSAIDs while drinking alcohol are at a higher risk of developing complications such as gastrointestinal bleeding. Therefore, it is advised that patients with rheumatoid arthritis should not engage in long-term heavy drinking. (Medication should be used under the guidance of a doctor.)

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Written by Guan Yu Hua
Orthopedic Surgery
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Difference between arthritis and rheumatoid arthritis

Arthritis is typically osteoarthritis, a chronic inflammation characterized primarily by degenerative changes in joint cartilage, followed by bone proliferation, making it a chronic disease. Early pathological changes include alterations in joint cartilage, such as subchondral bone extrusion, followed by changes in the muscles surrounding the periosteum and joint capsule. Early radiographic examinations can provide a definitive diagnosis. Its symptoms primarily manifest as pain. For rheumatoid arthritis, it generally presents as morning stiffness and joint swelling and pain more severe than in the surrounding area, which can essentially confirm a diagnosis. It usually affects large joints such as the knee, shoulder, or wrist joints, typically presenting as migratory pain. A definitive diagnosis can usually be made by testing for rheumatoid factor, with an anti-O level exceeding 500 units. Additionally, there may be a slight increase in white blood cells, accelerated erythrocyte sedimentation rate, and elevated C-reactive protein. Examination of the synovial fluid shows increased white blood cells and neutrophils. In such cases, using anti-rheumatic drugs might suffice, but it’s also crucial to ensure rest and local heat application. These two types of arthritis fundamentally differ.

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Written by Yang Ya Meng
Rheumatology
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How to cure rheumatoid arthritis?

The treatment methods for rheumatoid arthritis mainly consist of three major categories. The first category is the use of anti-inflammatory and analgesic drugs, commonly including non-steroidal analgesics such as sustained-release diclofenac sodium tablets, and small doses of corticosteroids can also be used. For rheumatoid arthritis, the most important treatment is the choice of immunosuppressants. Commonly used immunosuppressants include methotrexate and leflunomide. After using these medications, it is necessary to regularly monitor blood routine tests and liver and kidney functions to check for possible side effects of the drugs. If the effects of the above oral medications are not satisfactory, the application of biologics can also be considered. (Specific medications should be used under the guidance of a doctor, do not self-medicate.)

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Written by Yang Ya Meng
Rheumatology
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How long does it take to cure rheumatoid arthritis?

The symptoms of rheumatic arthritis, such as joint swelling and pain, generally improve on their own within about two weeks, with the longest duration not exceeding one month. However, since rheumatic arthritis is triggered by a Streptococcus infection, if the Streptococcus infection is not actively controlled, it is easy for the arthritis to relapse after the joint pain has improved. Therefore, for patients with rheumatic arthritis, it is essential to treat the Streptococcus infection early. Treatment with second-generation cephalosporin antibiotics for 10-14 days is recommended, followed by regular long-acting benzathine penicillin treatment at outpatient clinics to achieve a complete cure of rheumatic arthritis. (Specific medications should be used under the guidance of a doctor.)