For lupus, register under the department of Rheumatology.

Written by Zhang Lin
Rheumatology and Immunology Nephrology
Updated on September 09, 2024
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Patients with lupus should visit the Department of Rheumatology and Immunology, as lupus is a clinically complex autoimmune disease. Many people think that lupus is a skin disease, but this is not the case. Lupus is a rheumatic and immunological disease, belonging to the category of rheumatic immunological diseases, and is an uncommon autoimmune disease.

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Systemic lupus erythematosus has several symptoms, including:

Common manifestations of lupus include facial butterfly rash, discoid rash, photosensitivity, joint pain or arthritis, mental symptoms, recurrent oral ulcers, hair loss, foamy urine, etc. Patients with mesenteric vasculitis as the initial symptom mainly complain of abdominal pain and bloating. If the hematological system is the initial symptom, the main complaint is usually fatigue. If the patient presents with a seizure as the initial symptom, the main manifestation is limb convulsions. The heterogeneity of lupus is strong, and different patients can exhibit completely different clinical manifestations.

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Written by Zhang Lin
Rheumatology and Immunology Nephrology
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What should I do about lupus joint pain?

In patients with systemic lupus erythematosus, most suffer from arthralgia. The joint pain caused by systemic lupus erythematosus is due to the deposition of immune complexes in the joint cavity, or inflammation of the blood vessels nourishing the joints. This primarily manifests as joint swelling and pain, and often occurs symmetrically. When joint pain occurs in lupus, in addition to corticosteroid therapy, we can also use non-steroidal anti-inflammatory drugs (NSAIDs) under the guidance of a doctor. These drugs can achieve good analgesic and anti-inflammatory effects. However, patients with renal insufficiency should use these drugs with caution.

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Written by Zhang Lin
Rheumatology and Immunology Nephrology
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Will the rash of lupus fade away?

Patients with lupus often experience recurrent, stubborn skin lesions on their hands or face, and some may even develop ulceration, atrophy, or scarring on top of the existing erythema. Most lupus patients exhibit erythema, centered around the bridge of the nose and appearing on the cheeks. The lesions are disc-like on both sides with generally clear boundaries, either flat or slightly raised, and are categorized as exudative inflammation. Depending on the severity of the inflammation, the erythema can range from light red, bright red to purple-red. In severe cases, localized edema resembling erysipelas may occur, and scaling and hyperpigmentation may appear as the inflammation subsides. Facial rashes generally resolve, and most rashes do not leave marks after resolution. If hyperpigmentation remains after the erythema has resolved, it suggests a good prognosis. However, erythema in other areas, such as acral erythema and reticular cyanosis, may last for varying durations depending on the patient's individual condition.

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Written by Zhang Lin
Rheumatology and Immunology Nephrology
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What should I do if I have a fever with lupus erythematosus?

When patients with lupus experience fever, the fundamental approach is the use of ample steroids or other immunosuppressive drugs for treatment, which generally can quickly normalize body temperature. However, some patients may also experience fever during steroid use, possibly due to the steroids reducing immune function and inducing a bacterial infection. At this point, it is necessary to find evidence of infection and promptly treat with adequate sensitive antibiotics. Then, there will certainly be questions about why patients with lupus who have a fever cannot use antibacterial drugs or antipyretics. This is because fever in lupus patients is often an important indicator of disease activity. During acute phases, the fever is typically high, not caused by external infections, thus antibacterial drugs are ineffective. Using antipyretics can temporarily normalize body temperature, but once the effect of the medication wears off, the high fever may recur. Patients with lupus should not casually use medications. If medication is needed, it should be used under the guidance of a doctor.

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Written by Zhang Lin
Rheumatology and Immunology Nephrology
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Lupus erythematosus taking steroids side effects

Patients with lupus mainly use steroid treatment, but steroids have many side effects during their application, such as increased blood pressure, inducing or exacerbating infections, inducing or aggravating peptic ulcers, necrosis of the femoral head, osteoporosis and vertebral compressive fractures, delaying wound healing in injured patients, increasing blood sugar, etc. Additionally, steroids can cause nervous sensitivity, agitation, insomnia, emotional changes, and even apparent mental symptoms, inducing seizures such as epilepsy. Some patients may also have suicidal tendencies. Therefore, it is necessary to use medication rationally under the guidance of a doctor, reduce the dosage timely, and effectively prevent and treat to minimize the occurrence of side effects. Taking steroids can also lead to weight gain; hair loss is relatively less common. The occurrence of side effects varies among individuals and should be tailored to the patient's specific condition.