Malignant lymphoma follow-up checks

Written by Liu Liang
Oncology
Updated on July 01, 2025
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Malignant lymphoma, because it occurs in lymph nodes or tissues and organs of the lymphatic system, is a type of malignant tumor that can invade parts all over the body. Therefore, for the follow-up examination of lymphoma, the most commonly used method is PET-CT, which is a very good method for follow-up examination. If the patient does not have the conditions to undergo PET-CT, a whole-body enhanced CT scan from head to toe can also be done, which is also relatively common. However, for some special lymphomas, such as patients with gastric mucosa-associated lymphoma, they need to undergo a gastroscopy for their follow-up. For patients with nasal cavity NK/T-cell lymphoma, they need to undergo enhanced MRI of the nasopharynx and neck area. Therefore, the most commonly used method for follow-up examinations of malignant lymphoma is still PET-CT.

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Is lymphoma hereditary?

Lymphoma is generally not hereditary, as it is not a genetic disease. However, I must mention that most neoplastic diseases do have some hereditary factors to some extent. The reason for this is that the cause of lymphoma is currently unclear, and it may be related to genetic mutations, which raises the issue of heredity. Another point is that heredity often refers to transmission among direct relatives. This means there could be a problem in that you might share similar environments and lifestyles, including diet. If there are factors in your diet or living environment that could trigger lymphoma, and you are both exposed to these factors, then your probability of developing lymphoma could indeed be higher than in patients without a family history, leading to such a concern.

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Is lymphoma a cancer?

Cancer actually refers to malignant tumors. Malignant tumors are named differently based on their site of origin. For example, those originating from epithelial tissue are called carcinomas, such as lung cancer, liver cancer, colon cancer, etc. Lymphoma refers to a malignant tumor originating from lymph nodes or tissues or organs outside the lymph nodes, which we call lymphoma. There are also some malignant tumors originating from mesenchymal tissue, which we call sarcomas. Therefore, lymphoma is also a malignant tumor and is considered a type of cancer.

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The pattern of fever in lymphoma

Fever symptoms are quite common in patients with lymphoma, which we refer to as B symptoms. The pattern of their fevers is primarily low-grade, occurring more frequently in the afternoon or evening. Unlike ordinary bacterial infections, fevers in these patients do not respond well to anti-inflammatory drugs, but they do respond better to steroid treatment for reducing fever. However, if the lymphoma is not under control, their fever will repeatedly recur. Corresponding cooling treatments can reduce the temperature, but the fever will reoccur repeatedly. Only when the lymphoma and tumor are under control will the fever symptoms start to improve.

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What are the early symptoms of lymphoma?

Lymphoma is a malignant tumor of the hematological system, with early symptoms including painless enlargement of the lymph nodes in the neck, which are generally well-movable and firm or hard in texture early on, without inflammatory changes such as redness, swelling, heat, or pain. Additionally, lymphomas occurring in the gastrointestinal tract can clinically present with symptoms such as upper abdominal fullness and discomfort, bloating, nausea, recurrent acid reflux, and belching. Lymphomas occurring in the respiratory system can manifest clinically with symptoms such as cough, shortness of breath after activity, and chest pain. Lymphomas occurring in the brain can cause dizziness, headaches, movement disorders, ataxia, and abnormal gait.

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Is lymphoma a type of cancer?

Cancer refers to malignant tumors. Tumors are classified into benign and malignant types, with the malignant ones commonly referred to as cancer. Often discussed are those originating from epithelial cells, termed carcinomas, such as lung cancer and breast cancer. However, there are special types such as those originating from mesenchymal tissue, called sarcomas, including synovial sarcoma and osteosarcoma, which are also malignant tumors and belong to cancer. Lymphoma, a malignant tumor originating from lymph nodes or extranodal tissues or organs, is also classified as cancer.