Precursors of uremia

Written by Li Liu Sheng
Nephrology
Updated on February 14, 2025
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The kidneys have a very strong compensatory ability. When kidney function is slightly impaired, they can generally still handle the basic physiological functions of the human body through compensation, so patients may feel that everything is normal. Despite the fact that the occurrence and development of uremia is a long and gradually worsening process, which can sometimes be very severe, it is still possible to detect early signs of uremia if one actively seeks them out early on. Early indications of uremia can be identified in time by going to the hospital for urine and blood tests. The early signs of uremia often manifest as general fatigue, which is the symptom most easily overlooked. Other symptoms of early uremia include edema, especially noticeable swelling of the eyelids and facial area after waking up in the morning. If it develops into systemic or persistent edema, the condition is already very serious. Additionally, early-stage uremia patients may also experience an increase in the frequency of nocturnal urination and more foam in the urine, as well as increased blood pressure, and even dizziness, headaches, and a lack of appetite. These are all early signs of uremia.

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Written by Li Liu Sheng
Nephrology
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How should uremia patients rest?

Adequate rest plays a very important role in the recovery of patients with uremia. If the condition of the uremia patient is in an acute phase, for example, if the patient feels palpitations, chest tightness, shortness of breath after activities, or even has obvious edema and high blood pressure, the patient should rest in bed and try to avoid getting out of bed. They should eat and take care of personal hygiene while in bed. If they feel chest tightness, they can also use oxygen. Once the condition of the uremia patient has stabilized, especially after undergoing hemodialysis treatment, and the symptoms of uremia have improved, they can rest out of bed and should ensure they get seven to eight hours of sleep daily. Only through sufficient sleep can the patient's mental state significantly improve. During the rest period, patients can also engage in appropriate recreational activities, such as outdoor walks, singing, and other activities.

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Can uremia be cured?

First, it is necessary to clarify the cause and the severity, so it is important to visit the nephrology department for comprehensive tests. Once the cause is determined, the next steps can be planned based on the results, and dialysis may be necessary if required. If there is no improvement, treatments such as kidney transplantation can be considered. It is also crucial to rest, avoid fatigue, reduce activities, especially strenuous activities, maintain a positive mood, adjust your mentality, and have regular follow-ups. Therefore, this issue needs to be actively addressed, as it can be very troublesome to manage and the prognosis may be very poor if not taken seriously.

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Written by Li Liu Sheng
Nephrology
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Causes of Uremia

Uremia is a syndrome caused by the progressive development of various chronic kidney diseases, eventually leading to renal failure in patients, where the kidneys are unable to promptly eliminate excess water, various electrolytes, and toxins from the body. There are many causes of uremia; chronic nephritis, diabetic nephropathy, and hypertensive nephropathy are the most common causes. Other causes include chronic tubulointerstitial nephritis, chronic pyelonephritis, chronic obstructive nephropathy, toxic nephropathy, hereditary nephritis, renal vascular diseases, and lupus nephritis. Once uremia occurs, the preferred treatment is dialysis therapy, which can be either hemodialysis or peritoneal dialysis. Only after dialysis treatment can the life of a patient with uremia be prolonged.

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Written by Guan Hai Fang
Urology
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Is uremia serious?

Uremia is very serious. For patients with uremia who wish to be cured, the current method is to undergo kidney transplantation. Kidney transplantation is currently considered the best method for treating uremia. If no suitable kidney source is found, or economic conditions do not allow, or for some other reasons, it is recommended that patients undergo dialysis. Dialysis is also quite expensive, but if economic conditions permit, and physical health and mood among other factors allow, patients with uremia who undergo regular dialysis can generally have their lives extended by several years. It is not uncommon to see reports of lives being extended by more than a decade.

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Can holding urine cause uremia?

Generally speaking, holding urine does not lead to uremia, but if the bladder is overfilled, it can result in an inability to urinate. This can lead to acute renal dysfunction. After catheterization, the indicators of renal function can quickly return to normal. Therefore, we should try to avoid holding urine as much as possible and go to the bathroom promptly when we need to. This is something we should pay attention to in our daily lives.