Is uremia serious?

Written by Guan Hai Fang

Urology

Updated on September 07, 2024

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Uremia is very serious. For patients with uremia who wish to be cured, the current method is to undergo kidney transplantation. Kidney transplantation is currently considered the best method for treating uremia. If no suitable kidney source is found, or economic conditions do not allow, or for some other reasons, it is recommended that patients undergo dialysis. Dialysis is also quite expensive, but if economic conditions permit, and physical health and mood among other factors allow, patients with uremia who undergo regular dialysis can generally have their lives extended by several years. It is not uncommon to see reports of lives being extended by more than a decade.

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What tests are involved in checking for uremia?

Uremia refers to the final stage of chronic renal failure, also known as end-stage kidney disease. Therefore, the first step in examining a patient with uremia is to check renal function. The patient's blood creatinine level must reach a certain level to diagnose uremia. Secondly, it is necessary to examine the urinary system through color Doppler ultrasound, and to conduct blood tests for routine blood indicators, electrolytes, parathyroid hormone, etc. The color Doppler ultrasound shows a reduction in kidney size, which provides evidence for the diagnosis of uremia. Patients with uremia often also suffer from various complications, including anemia, electrolyte disorders, hyperparathyroidism, and so on. Therefore, such patients also need to undergo examinations for routine blood parameters, electrolytes, and parathyroid hormone levels, among other indicators.

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Does uremia cause fever in its early stages?

Fever is not an early clinical manifestation in patients with uremia; therefore, patients in the early stages of uremia do not exhibit fever. Typically, in the early stages of uremia, patients only show symptoms such as fatigue, poor spirit, lack of appetite, and easy fatigue, and may experience edema, such as swelling of the eyes and facial area after waking up in the morning, making it difficult for patients to open their eyes, and swelling of the lower limbs. In addition, patients also exhibit high blood pressure, such as increased systolic and diastolic pressures, which are difficult to control. Patients often exhibit clinical symptoms such as dizziness and headache. Patients also experience a significant increase in the frequency of urination at night and an increase in urine output, which are all early manifestations of uremia.

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Is high creatinine uremia?

High creatinine levels do not necessarily indicate uremia. High creatinine often implies that the patient is experiencing renal failure, which can be classified into acute renal failure and chronic renal failure based on factors such as the patient's medical history and course of the disease. Uremia is the final state of chronic renal failure. Thus, even if high creatinine levels suggest the possibility of chronic renal failure, it does not necessarily mean that the patient has reached the final stage. Uremia, also known as end-stage renal disease, generally requires a patient's blood creatinine to exceed 707 µmol/L. Additionally, patients often simultaneously present with clinical manifestations such as renal anemia, disorders of calcium and phosphorus metabolism, and reduction in kidney size.

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Written by Li Liu Sheng

Nephrology

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Does uremia transmit to others?

Uremia is not contagious to others because it is not an infectious disease. Uremia is a severe renal failure, so patients with uremia can interact, communicate, live, work, and study with healthy people without the need for gastrointestinal or respiratory isolation. Normally, if a patient with uremia is stable, they can engage in sexual activities and the disease will not be transmitted through sexual contact. Uremia usually presents symptoms such as nausea, vomiting, edema, and increased blood pressure. Therefore, patients with uremia need to undergo dialysis treatment. They can choose either hemodialysis or peritoneal dialysis. Dialysis treatment can significantly improve the symptoms of uremia and enhance the quality of life of the patients.

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Is uremia hereditary?

Uremia is not actually an independent disease, so it's difficult to say that uremia is hereditary. Uremia refers to a condition where the kidneys are 90% damaged. However, there are many reasons that can cause more than 90% of kidney tissue damage; among these, some are genetic diseases, but most are not hereditary. Common causes of hereditary uremia include diabetes, as well as primary chronic glomerulonephritis, hypertension, urinary system stones, and even prostate tumors, allergic purpura, etc., which can all cause kidney damage. These factors are generally not genetic diseases. However, there are very few causes of uremia that are genetic diseases, mainly including autosomal dominant polycystic kidney disease.