Acute appendicitis is primarily diagnosed by pressing on McBurney's point in the lower right abdomen, as the appendix is located in the right iliac fossa in the vast majority of patients, and its surface projection is mainly at the outer third of the line connecting the umbilicus and the anterior superior iliac spine.

However, a very small number of people may experience situs inversus, where the appendix could possibly be located in the lower left abdomen. Tenderness at a fixed point in the lower right abdomen is often a specific diagnostic criterion for acute appendicitis in clinical practice. If most patients exhibit symptoms of peritoneal irritation, it indicates worsening appendicitis symptoms, possibly even gangrene perforation. Most patients who experience a course lasting more than 3-5 days can develop a mass in the lower right abdomen, indicating the formation of a periappendiceal abscess. In cases where the symptoms are manageable, conservative treatment strategies can be adopted. Traditional Chinese Medicine methods can be used to promote the absorption of inflammation, with an appendectomy scheduled three months later.