The difference between acute appendicitis and chronic appendicitis

Written by Ren Zheng Xin
Gastroenterology
Updated on May 26, 2025
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Acute appendicitis and chronic appendicitis are quite different. Acute appendicitis develops suddenly with clear symptoms of fever and vomiting, and the pain in the lower right abdomen is relatively severe. Chronic appendicitis, on the other hand, often develops as a result of prolonged acute appendicitis. The abdominal pain is not typically characteristic, generally with few instances of fever or vomiting, but it can include persistent abdominal pain. Chronic appendicitis can lead to the formation of an abscess around the appendix, and a lump can be felt in the lower right abdomen. Acute appendicitis generally requires prompt surgical treatment to prevent its transition into chronic appendicitis.

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Written by Ren Zheng Xin
Gastroenterology
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The cause of acute appendicitis

The etiology of acute appendicitis is directly related to obstruction and infection of the appendiceal lumen. The appendix, a narrow and elongated tube connected to the cecum, can develop increased luminal pressure due to obstruction, leading to disturbances in the blood supply to the appendiceal wall. This can easily cause damage to the mucosa and subsequent infection. Infection of the appendiceal lumen can directly cause acute appendicitis. Additionally, gastrointestinal dysfunction can also cause muscle and vascular spasms in the appendix leading to blood supply disturbances and the invasion of bacteria, resulting in acute inflammation. For acute appendicitis, surgical treatment should be administered immediately upon diagnosis.

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Written by Ren Zheng Xin
Gastroenterology
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acute appendicitis symptoms

The symptoms of acute appendicitis typically include abdominal pain at the onset of the condition, which initially occurs around the navel and then localizes to the lower right abdomen, as well as early nausea and vomiting caused by gastric spasms. Patients with more severe inflammation may also exhibit fever. If the inflammation spreads to the peritoneum, there will be tenderness at McBurney's point and rebound tenderness, along with tense abdominal muscles. Based on these symptoms, making a definitive diagnosis of acute appendicitis is not particularly difficult.

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Gastroenterology
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Early symptoms of acute appendicitis

The symptoms of the early stage of acute appendicitis primarily include vague abdominal pain, initially across the abdomen, then transitioning around the belly button, and after several hours, shifting to the lower right abdomen where the pain becomes localized. The early symptoms of acute appendicitis are not typically distinctive, with the onset being quite sudden, accompanied by severe abdominal pain, vomiting, and fever. Based on these typical clinical manifestations, diagnosing acute appendicitis is not difficult. Clinically, the main treatment is the surgical removal of the appendix, with laparoscopic appendectomy being the more common practice nowadays. This method involves less bleeding during the operation and a quicker post-operative recovery.

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Gastroenterology
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How to medicate for acute appendicitis

Acute appendicitis is commonly treated surgically in clinical settings. Medication for acute appendicitis should be used with caution according to indications; if the appendix is not purulent, it is appropriate to use anti-inflammatory drugs to control the infection and choose sensitive antibiotics, such as quinolones. If the appendix becomes purulent or perforates, timely surgical treatment should be administered to prevent further exacerbation of appendicitis. Before and after the surgery, it is important to monitor whether the patient's symptoms and signs have significantly worsened. (Medications should be taken under the guidance of a physician and based on actual conditions)

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Written by Ren Zheng Xin
Gastroenterology
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The Difference Between Acute and Chronic Appendicitis

The differences between acute appendicitis and chronic appendicitis mainly lie in the onset of the condition, physical signs, and laboratory tests. First, regarding the onset of the condition, acute appendicitis occurs suddenly and can involve abrupt abdominal pain, whereas chronic appendicitis often manifests as fixed tenderness in the lower right abdomen and the symptoms are not particularly typical. In terms of physical signs, acute appendicitis presents with migratory pain in the lower right abdomen, while chronic appendicitis generally does not involve rebound pain. Thirdly, concerning auxiliary examinations, acute appendicitis shows a significant increase in the white blood cell count during an attack, whereas in chronic appendicitis, the white blood cell count may appear normal.