Upper gastrointestinal bleeding clinical manifestations

Written by Wang Li Bing

Intensive Care Medicine Department

Updated on September 15, 2024

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Upper gastrointestinal bleeding primarily refers to bleeding above the Treitz ligament. The most common causes in clinical practice are peptic ulcers, rupture of esophagogastric varices, acute erosive hemorrhagic gastritis, gastric cancer, etc. The clinical manifestations of upper gastrointestinal bleeding mainly depend on the volume and speed of the bleeding, with the main symptoms being vomiting blood and black stools. After significant blood loss, patients may experience symptoms of peripheral circulatory failure due to reduced circulating blood volume, such as dizziness, palpitations, fatigue, cold limbs, increased heart rate, and low blood pressure. If the patient enters a state of shock, it could even be life-threatening.

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Written by Wu Hai Wu

Gastroenterology

45sec

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Upper gastrointestinal bleeding, vomiting blood, amount of bleeding.

Patients with upper gastrointestinal bleeding may experience vomiting blood once the stomach bleeding reaches more than 200 mL. The occurrence of vomiting blood also indicates a significant amount of bleeding. Therefore, patients who experience vomiting blood need to actively seek medical attention as soon as possible at the gastroenterology department of a reputable hospital. If the condition permits, a thorough examination with an electronic gastroscope should be carried out promptly to determine the cause, location, and amount of the bleeding. Endoscopic hemostasis can also be performed at the same time. If necessary, oral or intravenous medications that suppress gastric acid secretion can be administered, along with other comprehensive treatments.

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Written by Wu Hai Wu

Gastroenterology

48sec

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The cause of vomiting coffee-colored substances due to upper gastrointestinal bleeding.

Upper gastrointestinal bleeding results in the vomiting of coffee-colored blood because the combination of fresh blood with stomach acid forms a coffee-colored liquid. If the bleeding volume exceeds 200mL in a short period, coffee-colored vomit may occur. It is necessary to seek prompt medical attention at a regular hospital’s gastroenterology or emergency department. Adequate diagnosis with an electronic gastroscopy is essential to identify the source and location of the bleeding, and active endoscopic treatment should be undertaken. Additionally, it is crucial to actively replenish fluids, correct the loss of body water, and restore blood volume. Treatment should also include the use of proton pump inhibitors and gastric mucosal protectants.

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Written by Wu Hai Wu

Gastroenterology

53sec

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Will melena from upper gastrointestinal bleeding heal by itself?

Generally speaking, after the occurrence of black stool due to upper gastrointestinal bleeding, it is quite difficult to cure and requires active treatment measures. For example, it is necessary to perform thorough gastroscopy and under gastroscopy, endoscopic treatment can be conducted. It is also advisable to consider oral medications that inhibit gastric acid secretion and protect the gastric mucosa. Medications that inhibit gastric acid secretion include proton pump inhibitors (PPIs) such as omeprazole, lansoprazole, and pantoprazole. Alternatively, H2 receptor antagonists such as ranitidine and famotidine can be selected. In terms of efficacy, proton pump inhibitors are generally more effective and better than H2 receptor antagonists, with fewer side effects.

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Written by Wang Li Bing

Intensive Care Medicine Department

1min 9sec

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Is upper gastrointestinal bleeding dangerous?

Upper gastrointestinal bleeding is life-threatening if the amount and speed of bleeding are substantial. Therefore, proactive and effective measures should be taken to rescue the patient. Generally, after anti-shock treatment and rapid blood volume replenishment, the patient's life can be saved. The main clinical treatment measures include the following: First, keep the patient in a recumbent position at rest, ensure that the airway is clear, and prevent blood aspiration due to vomiting. Second, during the bleeding period, it is necessary to enforce fasting, closely monitor the patient's vital signs, such as heartbeat, breathing, blood pressure, consciousness, etc. Third, after hospitalization, it is crucial to actively replenish blood volume, such as transfusing compatible red blood cells, plasma, cryoprecipitate, etc., for fluid expansion. Drugs like proton pump inhibitors and octreotide can be used for hemostasis. If conditions permit, a gastroscopy can be performed to stop the bleeding, and surgical treatment may be considered if necessary.

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Written by Zhu Dan Hua

Gastroenterology

1min 26sec

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Clinical manifestations of upper gastrointestinal bleeding

Patients with upper gastrointestinal bleeding typically present with vomiting blood or bleeding from the stool. Of course, if the bleeding amount is small, there may be no other discomfort. However, if the bleeding is significant, symptoms may include dizziness, fatigue, chest tightness, and palpitations related to low blood volume. Some patients might also experience abdominal discomfort, such as abdominal pain, bloating, or even indigestion. For those suspected of upper gastrointestinal bleeding, it is advisable to further complete blood tests, stool analysis, and electrocardiograms. It is necessary to promptly carry out a gastroscopy when needed to clarify the cause of the bleeding, and consider if it is due to ulcers or vascular malformations. In the early stages of treatment, symptomatic management should be prioritized, and patients are advised to actively rehydrate to improve symptoms of low blood volume and to transfuse red blood cells if necessary to correct anemia. Once the cause is identified, causative treatment should be added, such as the use of acid-suppressing and gastric-protecting drugs for bleeding associated with peptic ulcers. (The use of medications should be under the guidance of a doctor.)