Melanoma brain metastasis symptoms

Written by Sun Ming Yue
Medical Oncology
Updated on May 24, 2025
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If there are symptoms of melanoma brain metastasis, patients generally display symptoms of increased intracranial pressure, typically manifesting as headaches accompanied by nausea, vomiting, papilledema, and localized neurological deficits. The tumor in the brain substantively invades the ventricles, easily causing symptoms such as hemiplegia, aphasia, and psychiatric symptoms in patients. If the melanoma occurs in the spinal cord, it can easily lead to segmental sensory and motor disturbances and subarachnoid hemorrhage of the spinal cord. If patients suddenly experience disturbances in consciousness or vomiting, some may develop brain herniation, which is very dangerous. It is recommended that patients seek timely treatment.

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Melanoma check what items

If patients suspect that they have melanoma, they must go to a qualified hospital for examination. The diagnosis of melanoma mainly relies on visual inspection of colored moles that vary in color and shape, which can be directly observed with the eye. Also, if previously existing moles have enlarged or changed shape recently, these are signs that we need to pay attention to. If patients are suspected of having melanoma after a diagnosis, it is recommended to perform a complete excisional biopsy of the lesion, followed by a pathological examination after the surgery.

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How long does it take for melanoma to develop?

The duration of melanoma development varies because melanoma is a type of skin cancer with a relatively high degree of malignancy. However, clinically, the types of melanoma are diverse, and the onset time generally correlates with the patient's clinical phenotype. For some superficial types of melanoma with low malignancy, it generally takes several years to develop. For highly malignant melanomas, the disease generally progresses rapidly within about six months to a year. Once melanoma progresses, it can affect multiple parts of the body and severely impact the patient's lifespan.

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Does melanoma feel painful when pressed?

Melanoma is a highly malignant skin cancer, and clinically, some patients may experience pain when pressing on the lesion area. The reason for the pain is mainly due to the rapid growth of the melanoma, leading to compression of local tissues or the optic nerve and urgency, resulting in a painful sensation. This pain can exist even without pressing, and ulcerative lesions can occur in some affected areas, leading to symptoms such as pain, bleeding, and infection. In addition to pain upon local compression, patients with melanoma may also experience inflammatory changes such as redness, swelling, heat, and pain, causing some clinical symptoms of fever.

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Can melanoma without metastasis avoid chemotherapy?

For patients with melanoma that has not metastasized, direct surgical removal can be performed, and chemotherapy is not necessary after surgery. Melanoma is a malignant tumor that originates from melanocytes and can occur in many parts of the body, with melanomas of the skin and mucous membranes being the most common, accounting for about 70% of all cases. Once melanoma is diagnosed, if there is no distant metastasis to other organs, curative surgical removal can be performed. Postoperative treatment mainly involves immunotherapy, not systemic chemotherapy. For patients who are diagnosed with distant organ metastasis, systemic chemotherapy and immunotherapy are required.

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Is melanoma cancer?

Melanoma is generally a malignant tumor caused by melanin in the skin and other organs, which means melanoma is also known as cancer, and it is a very bad tumor. If there are hair follicles in this melanoma, then it is very likely that cancerous changes will occur. Patients should pay attention as the malignancy of the disease is extremely high, and they should seek timely medical examinations and treatment.