Osteosarcoma imaging manifestations

Written by Wang Cheng Lin
Orthopedics
Updated on December 23, 2024
00:00
00:00

The radiological features of osteosarcoma start with an introduction to X-ray imaging. X-rays can show typical new bone formation and bone destruction, which are characteristic features of X-rays. Destruction of bone trabeculae can also be seen on X-rays. Additionally, the density of the tumor tissue increases, leading to a characteristic X-ray known as the Codman's triangle, which occurs when the tumor penetrates the bone and pushes up the periosteum, creating a unique image of Codman's triangle. The second examination includes CT scans and MRI, which are primarily used to determine the nature and extent of the bone tumor, and whether there is infiltration into the surrounding soft tissues. The third radiological examination is a nuclear bone scan, which is primarily important for determining whether the myeloma has metastasized to distant sites.

Other Voices

doctor image
home-news-image
Written by Na Hong Wei
Orthopedics
1min 25sec home-news-image

Can osteosarcoma occur on the knee?

Can osteosarcomas grow on the knee? In fact, the locations where osteosarcomas commonly appear are indeed near the knee. There are mainly three common sites: the most prevalent is the distal end of the femur, the lower part of the thigh bone. The second most common site is the proximal end of the tibia. The third is the proximal end of the humerus. Therefore, osteosarcomas usually do grow near the knee. What are the symptoms of an osteosarcoma? The symptoms of osteosarcoma include, first, localized pain, which is a constant pain that persists, worsens, and does not alleviate, often causing night pain, and many patients do not feel pain during the day, only at night. The second symptom is a localized lump, generally spindle-shaped, with an increased skin temperature over the surface, and even distended veins due to the tumor restricting nearby joint movement. The third symptom is the appearance of cachexia or wasting syndrome throughout the body. The fourth point is that the growth of the osteosarcoma leads to erosion of the bone and eventually pathologic fractures. Thus, the likelihood of osteosarcomas appearing near the knee is very high, and many patients typically come to the hospital because of painful lumps near the knee, and then, after examination, the diagnosis is confirmed.

doctor image
home-news-image
Written by Na Hong Wei
Orthopedics
1min 10sec home-news-image

What is osteosarcoma?

Firstly, osteosarcoma is a common type of malignant tumor, characterized by a mechanism that produces bone-like tissue. It has multiple subtypes and can also develop into a secondary osteosarcoma. Secondly, it commonly occurs in adolescents. Thirdly, it typically affects the proximal femur, distal tibia, and proximal humerus. Fourthly, common osteosarcomas are generally spindle-shaped, often located near joints. The surface may have elevated skin temperature and sometimes superficial vein distension is apparent. It often involves the entire bone, including the periosteum, cortical bone, and bone cavity. Generally, the tumor appears as a very fine greyish-white or brownish-red fish-flesh-like change. Osteosarcoma is a malignant tumor and is particularly prone to lung metastasis. According to tumor staging, it is at least stage IIB, indicating that it should be detected, diagnosed, and treated early. The earlier the treatment, the better the outcome and the higher the five-year survival rate.

doctor image
home-news-image
Written by Wang Cheng Lin
Orthopedics
41sec home-news-image

Causes of Osteosarcoma Formation

The causes of osteosarcoma formation are currently unclear in clinical practice, but they are somewhat related to environmental factors and genetic changes, including heredity. If triggered by external viral infections or physical and chemical influences, osteosarcomas may develop. Likewise, genetic mutations and cellular mutations might also be associated with the formation of osteosarcomas. Osteosarcomas originate from mesenchymal cells and can grow rapidly; passing through a cartilaginous stage, they directly and indirectly form bone-like and bone tissues, damaging the bone structure, which leads to severe consequences.

doctor image
home-news-image
Written by Na Hong Wei
Orthopedics
55sec home-news-image

Osteosarcoma bone metastasis symptoms

The symptoms of osteosarcoma metastasis, osteosarcoma most commonly metastasizes to the lungs. If pulmonary metastasis occurs, there are at least two prominent characteristics. The first is that most metastatic tumors are located on the surface of the lungs and are rarely within the lung parenchyma, thus, they are not difficult to detect. The second point is that most metastatic tumors predominantly present as multiple bilateral lung metastases. Isolated unilateral lung metastasis is very rare. Therefore, this characteristic determines that osteosarcoma lung metastasis can only be managed with local wedge-shaped or segmental lung resections as the basic comfort measure. In fact, this simple surgical approach often allows for complete removal of the metastatic tumors while preserving most of the normal lung tissue.

doctor image
home-news-image
Written by Wang Cheng Lin
Orthopedics
32sec home-news-image

The common sites of osteosarcoma

Osteosarcoma commonly occurs in the long tubular bones of the limbs, such as the femur, tibia, and humerus, especially near the joints of these long bones where the incidence is highest. In children, the distal femur and proximal tibia account for about three-quarters of all bone tumors. Osteosarcoma can also occur in the proximal humerus, the spine, and the ribs, although it is less common in these locations. The most frequent sites remain the long tubular bones in the limbs.