For the examination of osteosarcoma, the first step is to take an X-ray, which can show changes in the bone quality. At the same time, it is necessary to perform a CT scan or MRI to clarify the nature of this bone tumor and its extent, or whether there is any distant metastasis. The third method is a nuclear bone scan, which mainly detects whether there are any early distant metastatic lesions. Of course, in clinical practice, the gold standard for diagnosing osteosarcoma relies on the examination of living tissue. That is, to perform a surgery, carry out a minor operation to obtain a little tissue from the bone tumor, and then send it for pathological examination to determine the nature of the tumor. This is the gold standard for diagnosing osteosarcoma.