Patients with osteosarcoma will not have red skin. The early symptoms of osteosarcoma are generally not obvious, primarily involving localized swelling, with pain around the joints leading to limited joint mobility. As the condition progresses, this pain may shift from intermittent to constant, and the severity of the pain will increase as the disease worsens. The second patient will exhibit a noticeable lump that can be felt; this lump is usually accompanied by significant tenderness. The third symptom is intermittent limping, caused by pain from the tumor during walking, which prevents the patient from bearing weight for extended periods. The fourth aspect involves systemic symptoms common to patients with tumors, such as anemia, mild fever, and even pathological fractures.