Can tertiary syphilis be transmitted?

Written by Zhu Zhu

Dermatology

Updated on April 14, 2025

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Third-stage syphilis is contagious, but its infectivity is weaker compared to first-stage and second-stage syphilis. However, the damage caused by third-stage syphilis is very severe, often causing damage to tissues and organ functions. It can potentially cause disabilities, deformities, or even life-threatening conditions. Therefore, the characteristic of third-stage syphilis is its weak infectivity but strong damaging effects. Thus, it is crucial to take third-stage syphilis seriously and seek regular and timely treatment.

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Written by Zhu Zhu

Dermatology

43sec

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Can you still have children with third-stage syphilis?

Third-stage syphilis is the most severe stage of the disease, and it is not possible to have children if one has third-stage syphilis, because syphilis can be transmitted from mother to fetus. The infectivity is particularly strong during the third stage. If a child is conceived at this time, it could lead to stillbirth. Besides stillbirth, even if the child is born by chance, they may have abnormal development or be born with diseases. This is tremendously painful and tormenting for both the parent and child. Therefore, one cannot have children with third-stage syphilis.

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Written by Qu Jing

Dermatology

1min 58sec

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How long is the latency period of syphilis?

Syphilis is a chronic infectious disease caused by the bacterium Treponema pallidum (TP), primarily transmitted through sexual contact and blood. The impact of syphilis is significant as it can affect all bodily tissues and organs, or can be transmitted through the placenta, leading to stillbirth, miscarriage, premature birth, and congenital infections. When syphilis is suspected, due to its complex clinical manifestations, a detailed medical history should be taken, a thorough physical examination conducted, and repeated laboratory tests performed to ensure an early and accurate diagnosis. It is important to trace back to any unprotected sexual contacts within the last six weeks and to routinely screen the sexual partners of patients for syphilis as well. Syphilis is divided into three stages: The diagnosis of primary syphilis is mainly based on the history of exposure, the incubation period (six weeks), typical clinical manifestations, and laboratory tests, noting that a negative syphilis serology result alone should not exclude the diagnosis of syphilis. The diagnosis of secondary syphilis primarily relies on the history of exposure, typical clinical manifestations, especially skin and mucosal lesions, combined with laboratory tests. The diagnosis of tertiary syphilis is mainly based on the history of exposure, typical clinical manifestations, and laboratory tests. Neurosyphilis can also be assessed through cerebrospinal fluid examination. Congenital syphilis primarily requires a maternal history of the disease, combined with typical clinical manifestations and laboratory tests for diagnosis.

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Written by Zhu Zhu

Dermatology

30sec

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Third-stage syphilis has no symptoms.

Once tertiary syphilis has developed, it is highly unlikely for there to be no symptoms. Tertiary syphilis is a late stage of the disease, generally involving the skin, mucous membranes, cardiovascular system, and even the motor and nervous systems. If there are no symptoms present, it is generally not possible to be in the tertiary stage of syphilis. Therefore, if tertiary syphilis occurs, it will not be without symptoms.

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Written by Luo Hong

Dermatology Department

49sec

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Can syphilis be completely cured?

Syphilis can generally be completely cured nowadays, except neurosyphilis which is somewhat harder to treat, as ordinary syphilis is curable and neurosyphilis may relapse occasionally. However, most current cases of syphilis fall into categories of latent, primary, or secondary syphilis. Tertiary syphilis is less common, and forms such as neurosyphilis and osteal syphilis belong to this stage. Therefore, when treated at a regular hospital with a standard treatment regimen, primarily using penicillin, administered as a long-acting intramuscular injection once a week, the recommended course of treatment usually consists of three to four weeks. If there is an allergy to penicillin, doxycycline can be used as an oral substitute for half a month.

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Written by Zhang Xiu Rong

Obstetrics and Gynecology

53sec

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Which department should women go to for syphilis testing?

For female syphilis screening, one generally needs to visit the department of venereal diseases, where hospitals with such departments conduct syphilis tests. The test for syphilis involves a blood draw for the RPR syphilis virus test. Through this testing, one can determine whether they have contracted syphilis. If a syphilis infection is detected, it is essential to choose the appropriate medication based on the test results for targeted treatment. Generally, both AIDS and syphilis fall under the purview of the venereal disease department. Therefore, if you wish to undergo syphilis testing, you must visit the venereal disease department of a hospital for the relevant examinations. Typically, there is an incubation period, and if the results are completely negative after three months, it generally means there is no significant concern.