Because tetanus antitoxin can effectively prevent infections caused by Clostridium tetani, it is generally used for preventative purposes and tends to be ideal in effect. The effect of this medication is usually noticeable within a week, and after that, it may not achieve the desired effect. Therefore, when tetanus antitoxin is administered, it is generally not advisable to drink alcohol within 7 days. After this period, normal alcohol consumption is possible, but excessive drinking should still be avoided.

Excessive alcohol consumption can potentially lead to a decrease in immunity. A decrease in immunity may facilitate bacterial growth, which could increase the likelihood of a Clostridium tetani infection and potentially impact the effectiveness of the tetanus vaccine. Thus, it is advisable to avoid alcohol during the first week to prevent any direct impact.