What is the function of a tetanus shot?

Written by Xu Jun Hui
General Surgery
Updated on January 01, 2025
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The function of the tetanus shot is to activate the body's immune system to produce antibodies that can specifically bind to the tetanus toxin, preventing the toxin from binding with nerve cells and causing a toxic reaction that could lead to respiratory arrest, asphyxiation, and endanger life safety. Tetanus infection occurs when the Clostridium tetani bacteria enter the body through mucous membranes following an injury, producing toxins that affect certain muscle groups, such as the jaw and respiratory muscles, thus threatening life safety. Therefore, the role of the tetanus shot is to produce antibodies that bind to the tetanus toxin, preventing it from producing a toxic reaction with nerve cells. Thus, if some wounds are deep and heavily contaminated, it is essential to undergo anti-tetanus treatment.

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Written by Gao Sen
General Surgery
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Tetanus 0.1ml how many units

In general, the dose of tetanus toxoid is 1500 international units per dose, approximately 1 ml per dose, and generally about 150 international units per 0.1 ml, which can be referred to the instructions. The use of tetanus toxoid should be avoided blindly and should be administered under the guidance of a physician. Additionally, wound cleaning and disinfection should be performed before administering tetanus toxoid. Furthermore, anti-infection treatment should be considered based on the contamination of the wound.

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Written by He Zong Quan
General Surgery
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Can a festering wound lead to tetanus?

Wound suppuration and contracting tetanus are two different concepts. Wound suppuration primarily occurs when there is an infection at the wound site, which spreads due to lack of significant control over the infection focus. We need to actively locate the infection source, perform thorough surgical debridement and drainage, use sensitive antibiotics as needed globally, and change dressings in a timely manner to manage the infection. Tetanus, on the other hand, is typically considered when the wound is too deep and visibly contaminated, often by rusty, sharp objects causing the infection. In such cases, thorough surgical cleansing of the wound is essential to prevent surface contamination, along with the systemic use of tetanus antitoxin to reduce or prevent a tetanus infection.

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Written by Xu Jun Hui
General Surgery
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Which department should I go to at the hospital for a tetanus shot?

Tetanus shots should be administered at a regular hospital in the emergency department. There are two types of tetanus injections: one that requires a skin test, called tetanus toxoid, and one that doesn't require a skin test, called tetanus immunoglobulin. It is generally recommended to get the tetanus shot within 24 hours of injury, and it is best to avoid alcohol before the injection. Drinking can cause dilation and reddening of the skin's capillaries, which can affect the results of the tetanus skin test. Tetanus is usually caused by the invasion of Clostridium tetani into the body, a type of anaerobic bacterium. Thus, for wounds that are small, deep, and heavily contaminated, such as with dirt, rust, or in cases of open fractures, anti-tetanus treatment is essential, and a tetanus shot can be administered in the hospital's emergency department.

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Written by Li Jin Quan
General Surgery
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How long is a tetanus shot effective?

Tetanus generally refers to a specific type of infection caused by the entry of tetanus bacillus into the body through broken skin or mucous membranes, where it produces a large amount of toxin. Typically, the incubation period for tetanus is 6 to 7 days, but it can be as short as within 24 hours or as long as several months or even years. Therefore, if there is a wound, the first thing to do is to clean the wound with hydrogen peroxide or saline. Then, it is best to go to the hospital to get a tetanus vaccine within 24 hours. If the tetanus vaccine is not administered within 24 hours, it can still be effective if given within a week.

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Written by Ma Xian Shi
General Surgery
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How long does it take for tetanus to develop?

Tetanus is an acute, specific infection caused by the invasion of Clostridium tetani into a human wound, where it grows and reproduces, producing toxins. Tetanus is a Gram-positive, anaerobic, spore-forming bacillus that is widely present in the external environment. Tetanus occurs only when tetanus bacillus grows and reproduces locally in a wound and produces exotoxins, which are the cause of the disease. The toxins of tetanus include spasm toxin and hemolysin. The incubation period of tetanus generally ranges from six to ten days. In some cases, it can occur within 24 hours or take as long as 20 to 30 days, or even months, particularly following the removal of foreign bodies or shrapnel. Neonatal tetanus generally occurs seven days after umbilical cord separation, clinically also known as the "seven-day wind." Generally, the shorter the duration of the incubation period or prodromal symptoms, the more severe the symptoms and the higher the mortality rate.