Can tetanus be fatal?

Written by Li Jin Quan
General Surgery
Updated on September 12, 2024
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Tetanus can be fatal if not treated promptly. When infected with tetanus, early symptoms primarily include dizziness, headache, fatigue, decreased appetite, weak chewing, and sore jaw muscles, some may also exhibit increased reflexes or muscle rigidity. As the condition worsens, some patients show typical tetanus symptoms such as lockjaw, difficulty opening the mouth, risus sardonicus, opisthotonos, and stiff neck. As the condition further deteriorates, it can lead to difficulty breathing, or even respiratory arrest, and cardiac arrest. If not promptly rescued, the patient can die.

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Written by Xu Jun Hui
General Surgery
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Does a tetanus shot hurt?

The tetanus shot causes slight pain. The injection site is in the muscle of the buttocks, where the pain is mild and tolerable. The purpose of the tetanus shot is to prevent infection by the tetanus bacillus, which tends to thrive in anaerobic conditions and in heavily contaminated wounds, such as those with soil and rust. Therefore, patients with deep wounds contaminated with soil or rust must receive anti-tetanus treatment. Additionally, it is important to promptly treat and dress wounds to prevent infection by the tetanus bacillus and to prevent wound infection. The pain from the tetanus shot is minor.

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Written by Xu Jun Hui
General Surgery
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How to administer an injection if the tetanus skin test is negative

A negative tetanus skin test indicates that there is no allergy to tetanus antitoxin, and 1500 to 3000 units of tetanus antitoxin can be directly administered via intramuscular injection in the upper arm or buttock. If the wound is heavily contaminated or the injection is not timely, the dose may be doubled or tripled at discretion, and it is also necessary to clean and dress the wound. The purpose of administering tetanus antitoxin via intramuscular injection is to prevent infection by Clostridium tetani. Therefore, patients with heavily contaminated or deep wounds must receive tetanus antitoxin treatment.

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Written by Xu Jun Hui
General Surgery
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Which part of the body is the tetanus shot administered?

Tetanus shots are administered in the buttocks or the muscular part of the upper arm, typically given as a muscle injection. Tetanus shots must not be administered intravenously. Before administering a tetanus shot, a skin test is conducted. If the skin test is positive, it is necessary to switch to a tetanus immune globulin that does not require a skin test; if the skin test is negative, a muscle injection can be performed. Tetanus is caused by the colonization of Clostridium tetani in the human body, producing neurotoxins, leading to a specific type of infection. Therefore, if the wound is deep and heavily contaminated, it is essential to promptly treat with a tetanus shot.

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Written by Li Xiao Lin
Emergency Department
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How to treat mild tetanus?

The treatment for mild tetanus mainly includes the following aspects: First, to control convulsions, diazepam or midazolam can be administered via muscle injection or intravenous injection. If necessary, phenytoin sodium can be combined to control seizures. If the convulsions last a long time and the symptoms are pronounced, sedative medications can be continuously used to control the convulsions. Second, use large amounts of penicillin and anti-tetanus bacillus treatment to control the infection. Third, maintain a quiet indoor environment to reduce stimuli. Fourth, after the patient regains consciousness, attention should be paid to diet: avoid spicy and stimulating foods, do not smoke or drink alcohol, and it is advised to drink more water and eat more fresh vegetables and fruits. (Please use medication under the guidance of a doctor)

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Written by Zhang Peng
General Surgery
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What should I do if I drink alcohol with tetanus?

If there are high risk factors for tetanus infection after an injury, and alcohol has been consumed, it is generally advisable to wait until sobriety before conducting relevant skin tests. Currently, there is no clear research on the relationship between alcohol consumption and an allergy to tetanus antitoxin. It is not very clear whether alcohol impacts the results of a skin test, so it is safer to perform the test after sobering up. Since the consequences of a tetanus infection can be severe, and the tetanus injection itself carries a certain risk of anaphylactic shock, which can lead to multiple organ problems and even be life-threatening, it is generally safer to conduct the skin test after sobering up and then proceed with the timely injection treatment. If the skin test is positive, tetanus immunoglobulin should be chosen promptly.