How to administer an injection if the tetanus skin test is negative

Written by Xu Jun Hui

General Surgery

Updated on December 10, 2024

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A negative tetanus skin test indicates that there is no allergy to tetanus antitoxin, and 1500 to 3000 units of tetanus antitoxin can be directly administered via intramuscular injection in the upper arm or buttock. If the wound is heavily contaminated or the injection is not timely, the dose may be doubled or tripled at discretion, and it is also necessary to clean and dress the wound. The purpose of administering tetanus antitoxin via intramuscular injection is to prevent infection by Clostridium tetani. Therefore, patients with heavily contaminated or deep wounds must receive tetanus antitoxin treatment.

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Written by Xu Jun Hui

General Surgery

54sec

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Can I get a tetanus shot in the emergency room?

The injection of tetanus shots is performed in the emergency department of regular hospitals. Tetanus shots are divided into tetanus toxoid, which requires a skin test, and tetanus immunoglobulin, which does not require a skin test. If the skin test for tetanus toxoid is positive, indicating an allergy, it cannot be injected, and must be replaced with the slightly more expensive tetanus immunoglobulin. It is generally recommended to administer the injection within 24 hours after injury to prevent infection by Clostridium tetani. Clostridium tetani is an anaerobic bacterium. It is necessary to administer tetanus treatment for injuries that are deep, in anaerobic conditions, contaminated, heavily contaminated with soil, rust, open fractures, etc., since these conditions can be conducive to tetanus infection.

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Written by Ai Bing Quan

General Surgery

50sec

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Where to get a tetanus shot?

Tetanus can be treated in any department, but generally, after an injury, one would first go to the emergency room. Therefore, tetanus is very common in emergency medicine. Tetanus is a type of anaerobic bacterium that is ubiquitous in nature. If a person has a wound that is small and deep, the internal environment can become anaerobic, which easily leads to rapid proliferation of tetanus. At this point, it is necessary to inject tetanus immunoglobulin into such wounds. It is best done within 24 hours because after a long period, the tetanus bacillus might have already proliferated in the wound. A skin test should be performed before the injection, and the injection can only proceed if the skin test is negative. If the wound is relatively large and severe, it generally will not be infected by tetanus bacillus.

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Written by Tang Da Wei

General Surgery

41sec

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Is it necessary to get a tetanus shot?

Getting a tetanus shot is very necessary if a patient has had an injury or has wounds on the body. Without a tetanus shot, there might be a risk of tetanus infection. The main reason is due to the presence of tetanus bacillus spores in the natural environment, which could colonize within the wound if it's exposed. This can potentially lead to a tetanus infection. Severe cases can present with symptoms such as opisthotonos, breathing difficulties, suffocation, and could even lead to death. The tetanus shot involves injecting tetanus antitoxin into the patient's body, which is a form of passive immunity and can prevent some symptoms of tetanus infection.

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Written by He Zong Quan

General Surgery

51sec

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Can a festering wound lead to tetanus?

Wound suppuration and contracting tetanus are two different concepts. Wound suppuration primarily occurs when there is an infection at the wound site, which spreads due to lack of significant control over the infection focus. We need to actively locate the infection source, perform thorough surgical debridement and drainage, use sensitive antibiotics as needed globally, and change dressings in a timely manner to manage the infection. Tetanus, on the other hand, is typically considered when the wound is too deep and visibly contaminated, often by rusty, sharp objects causing the infection. In such cases, thorough surgical cleansing of the wound is essential to prevent surface contamination, along with the systemic use of tetanus antitoxin to reduce or prevent a tetanus infection.

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Written by Xu Jun Hui

General Surgery

44sec

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Is tetanus easy to infect?

Tetanus is not easily contracted.Tetanus bacilli belong to anaerobes, and are prone to occur in conditions where the wounds are deep, in an anoxic or low oxygen situation, heavily contaminated wounds such as with dirt or rust, and in cases of open fractures with large wounds. In these situations, tetanus bacilli can colonize the skin and mucous membranes, producing neurotoxins that lead to a series of complications. Therefore, anti-tetanus treatment must be conducted for wounds in an anaerobic environment, such as heavily arsenic-contaminated wounds.For routine wounds that are shallow and small, it is sufficient to change the dressing.