Pertussis prone age group

Written by Yan Xin Liang
Pediatrics
Updated on April 01, 2025
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Pertussis, also known as whooping cough, is an acute respiratory infectious disease caused by Bordetella pertussis. The main age group affected by this disease are infants and young children, with the highest susceptibility seen in children under five years old, particularly infants younger than one year. The incidence of this disease has significantly decreased due to the widespread implementation of pertussis vaccination. Clinically, the disease is characterized by a cough that gradually worsens, presenting as typical paroxysmal, frequent coughing, and frothy sputum, with a crowing echo in the cough. The course of the disease can last up to three months.

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Written by Li Jian Wu
Pulmonology
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Can whooping cough be cured?

Pertussis, the disease, can be cured with timely and proper treatment, so there's no need to fear. It's important to clear any concerns and understand this correctly. Pertussis is primarily an acute infectious respiratory disease caused by Bordetella pertussis or Corynebacterium diphtheriae. The main clinical approach is to prevent the disease by administering the DTP vaccine. Once infected, the disease is characterized by typical paroxysmal bouts of coughing, including spasmodic coughing, sometimes accompanied by a crowing inspiratory stridor, and in some cases, symptoms resembling a barking cough. It is called pertussis because the course of the disease is long, but there should be no excessive fear as it can be completely cured with prompt treatment.

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Written by Li Jian Wu
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The "hundred days" in whooping cough refers to what?

The whooping cough we refer to clinically is a type of respiratory infectious disease. The term "hundred days" relates to the duration of the disease, which is relatively long, sometimes approaching one hundred days, hence the name whooping cough. However, it does not necessarily mean that one will cough or be infected for such a long duration. The specific circumstances should be determined according to the number of infecting pathogens and the body's immune response. If the immune system is normal and the infection is minor, some patients can recover without medication. Once a severe infection is diagnosed, it is crucial to promptly use sensitive antibiotics and engage in timely anti-inflammatory and symptomatic treatment.

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Written by Li Jian Wu
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Pertussis and measles transmission pathways

Pertussis and measles are two types of diseases, both of which are respiratory infectious diseases. Pertussis is caused by Corynebacterium diphtheriae or Bordetella pertussis, while measles is an acute, infectious disease caused by the measles virus. Transmission mainly occurs through close contact with infected individuals and via airborne droplets, and it is commonly seen in infants and young children under the age of five. Prevention of these diseases is primarily through vaccination, and once the disease occurs, it is important to promptly treat the infection with anti-inflammatory or antiviral treatments, while also managing the symptoms accordingly.

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Written by Li Jian Wu
Pulmonology
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Can you still get whooping cough even if you have been vaccinated?

If the whooping cough vaccine is administered effectively and antibodies are produced, it generally prevents reinfection. However, if the vaccine is not administered according to the prescribed schedule, or if no antibodies are produced after the vaccination, exposure to this pathogen may still lead to infection. The disease is characterized by fits of coughing, which can cause blushing, runny nose, tears, nausea, and vomiting. Some children may also experience a barking cough and a crowing sound during inhalation.

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Written by Li Jian Wu
Pulmonology
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What are the symptoms of pertussis encephalopathy?

Pertussis encephalopathy typically presents with persistent high fever, projectile vomiting, nausea, and severe headaches, which are indicators of increased intracranial pressure. It is necessary to conduct timely auxiliary examinations such as cerebrospinal fluid tests and cranial MRI for diagnosis. In conjunction with clinical symptoms, medications to alleviate cerebral edema and reduce intracranial pressure should be chosen for symptomatic treatment. Typically, corticosteroids are needed during the acute phase, along with mannitol, sedatives, and other symptomatic treatments. Additionally, antibiotics should be used to eliminate the Bordetella pertussis bacterium, the pathogen responsible for the condition.