What are the characteristics of the onset of whooping cough?

Written by Li Jian Wu
Pulmonology
Updated on May 03, 2025
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Pertussis is characterized by its distinctive cough, featuring episodes of spasmodic coughing that is intense and can lead to redness in the face and ears, a runny nose, nausea, vomiting, and headaches, among other complications. Some infants and toddlers may also exhibit a bark-like cough and an inspiratory "crowing" sound. Clinically, it is most commonly seen in children under five years of age. Diagnosis requires testing such as pathogen culture, complete blood count, and chest X-rays. Targeted antibacterial and anti-inflammatory treatments are then administered accordingly.

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Written by Yan Xin Liang
Pediatrics
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Pertussis prone age group

Pertussis, also known as whooping cough, is an acute respiratory infectious disease caused by Bordetella pertussis. The main age group affected by this disease are infants and young children, with the highest susceptibility seen in children under five years old, particularly infants younger than one year. The incidence of this disease has significantly decreased due to the widespread implementation of pertussis vaccination. Clinically, the disease is characterized by a cough that gradually worsens, presenting as typical paroxysmal, frequent coughing, and frothy sputum, with a crowing echo in the cough. The course of the disease can last up to three months.

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Written by Li Jian Wu
Pulmonology
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Whooping cough is caused by what?

Whooping cough is a type of contagious disease, caused by infection with the Bordetella pertussis or Corynebacterium diphtheriae that causes respiratory infection symptoms. Its characteristics include paroxysmal, hormone-like coughing, commonly seen in clinical paediatrics. It presents specific cough sounds, such as a bark-like cough or a crowing sound during inhalation. If similar symptoms are observed, sputum culture or other diagnostic tests such as chest X-rays and routine blood tests can be performed. Once diagnosed, it is crucial to promptly select macrolide antibiotics to eliminate the pathogens.

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Written by Zeng Hai Jiang
Pediatrics
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How long does it usually take for the blood picture of pertussis to come down when it's too high?

Whooping cough is an acute respiratory infectious disease caused by Bordetella pertussis infection, commonly seen in children. The main clinical symptoms include typical paroxysmal spasmodic cough, crowing inspiratory whoop, with the cough being more prominent at night. In the peripheral blood, there will be a marked increase in white blood cell count, lymphocyte count, and lymphocyte classification. After a confirmed diagnosis of whooping cough, macrolide antibiotics are administered. After a week of aggressive treatment, the blood count typically decreases significantly.

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Written by Zeng Hai Jiang
Pediatrics
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Why is whooping cough milder during the day and worse at night?

Whooping cough is an acute respiratory infectious disease caused by Bordetella pertussis infection, commonly seen in children. The main symptoms are paroxysmal spasmodic coughing, a crowing inspiratory noise, with coughing occurring both during the day and at night, more significantly at night. The main reasons are as follows: first, the dry indoor air causes irritation. Second, during the night, the mucus secreted by the bronchial mucosa cannot be expelled from the body, which stimulates the bronchial nerves and triggers worsening cough symptoms. Coughing can also cause redness of the face and ears, runny nose, nausea, and vomiting.

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Written by Li Jian Wu
Pulmonology
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late stage symptoms of whooping cough

Pertussis, also known as whooping cough, is a highly contagious respiratory disease caused by the Bordetella pertussis or Corynebacterium diphtheriae bacteria. After infection, paroxysmal coughing occurs, and in later stages, the frequency of coughing episodes decreases and the duration of symptoms shortens. The main treatment should involve the use of macrolide antibiotics to eliminate the pathogen. Additionally, it is advisable to drink plenty of water, rest adequately, measure body temperature twice daily, and avoid excessive fatigue. As long as function and symptoms gradually ease, it indicates the recovery phase is beginning, generally requiring about fifteen to twenty days for complete recovery.