Is the pertussis vaccine an inactivated vaccine?

Written by Li Jian Wu
Pulmonology
Updated on April 09, 2025
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The pertussis vaccine is not an inactivated vaccine but a live attenuated vaccine, which primarily stimulates the body to produce antibodies. Once antibodies are produced, it can effectively prevent the disease pertussis. The commonly used pertussis vaccine in clinical settings is the trivalent vaccine, also known as the DTP vaccine, which can prevent pertussis, diphtheria, and tetanus—three infectious diseases caused by pathogens. It is essential to follow medical advice and complete the vaccination schedule as prescribed to achieve prevention. After vaccination, it is crucial to observe for any complications or adverse reactions.

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Is whooping cough easy to treat?

Whooping cough is treatable. This disease is a highly contagious respiratory tract infection common in children. Its main characteristics are paroxysmal, spasmodic coughing. Some children may also have a bark-like cough and a crowing sound during inhalation. It is important to correctly identify and check the pathogen, which could be due to infection by the diphtheria bacillus or the whooping cough bacillus. Typically, it can be treated with intravenous macrolide antibiotics or penicillin antibiotics to eliminate the pathogen, along with symptomatic treatment.

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After receiving the DTP vaccine, can you still get whooping cough?

The DTP vaccine is a combination of pertussis bacteria, diphtheria toxoid, and tetanus toxoid, which can prevent whooping cough, diphtheria, and tetanus simultaneously. The target group for the DTP vaccine is children aged 3 months to 7 years. The DTP vaccine requires three consecutive shots. Only after the three consecutive injections will sufficient antibodies be produced. However, these antibodies can only be maintained for a certain period of time and do not provide lifelong immunity. Many parents mistakenly think that once their child is vaccinated, they are invulnerable to all diseases, but this is an unscientific notion. The efficacy of vaccines is not 100%. The common basic vaccines currently used generally have an efficacy rate of over 80%, meaning that after vaccination, 80% of people will produce antibodies. However, since the antibody concentration of some vaccines can decrease significantly over time to a level that does not reach the immunity concentration, booster shots are necessary.

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How is whooping cough treated?

Pertussis, also known as whooping cough, is an infectious respiratory disease caused by the infection of Bordetella pertussis or Bordetella parapertussis. Clinically, it is characterized by episodes of sudden, rapid coughing, a bark-like cough, and an inspiratory "crowing" sound. It is also advisable to check the sputum culture to confirm the cause of the disease. In terms of treatment, in addition to symptomatic treatment, macrolide antibiotics should be selected and administered for at least about half a month. Options include intravenous drips of erythromycin injection or azithromycin injection.

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Written by Zeng Hai Jiang
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Whooping cough occurs in children of what age?

Pertussis is an acute respiratory infectious disease caused by Bordetella pertussis infection, mainly characterized by paroxysmal spasmodic coughing, crowing inspiratory stridor, and the coughing often occurs at night. Pertussis can occur in both adults and children, but is more common in children. Children under the age of five are the most susceptible, especially infants who have not been vaccinated against pertussis. Children are generally vaccinated with the primary prophylaxis at the age of three to five months, receive a booster at 18-24 months, and another booster at the age of six. If pertussis occurs in adults, the condition is milder and the course of the disease is shorter.

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Is whooping cough contagious?

Pertussis, a type of disease, is an infectious respiratory infection, thus it is contagious. If there is a pertussis patient in the home, it is recommended to isolate the patient for treatment, ensure air ventilation and disinfection in the living space, and use personal items separately. Patients should ideally wear masks to block the bacteria from spreading through respiratory passages, and should actively choose antimicrobial drugs to control the infection, drink plenty of water, and rest sufficiently. When feverish, adopt physical methods to reduce fever or take antipyretic medication for symptomatic treatment. The main principle should be to choose macrolide antibiotics to control the infection. (Please use medication under the guidance of a professional physician and do not self-medicate.)