What is the pertussis vaccine?

Written by Li Jian Wu
Pulmonology
Updated on May 28, 2025
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The pertussis vaccine we currently administer is a combination vaccine that primarily includes diphtheria, pertussis (whooping cough), and tetanus, commonly referred to as the DTP vaccine. It is generally administered for the first time when a baby is three months old, the second dose at four months of age, and the third dose at five months. A booster vaccine is given again when the child is one and a half to two years old to produce antibodies that can effectively prevent pertussis, a respiratory infectious disease. It is important to detect early, vaccinate in a timely manner, and prevent early.

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Written by Li Jian Wu
Pulmonology
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Is nebulization useful for pertussis?

Nebulized inhalation for localized treatment of pertussis can be quite effective. It helps alleviate bronchial smooth muscle spasms and is used for spasmodic coughs, effectively easing cough symptoms as a symptomatic treatment measure. However, it is also necessary to target the infectious pathogens with oral or intravenous macrolide antibiotics for anti-inflammatory treatment. Drinking plenty of water, maintaining suitable indoor temperature and humidity, and having confidence in overcoming the disease are important. Although the course of the disease may be long, complete recovery is possible through proper treatment, so there is no need for excessive worry.

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Written by Li Jian Wu
Pulmonology
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Whooping cough is transmitted through respiratory droplets.

Pertussis is mainly transmitted through airborne droplets and is a commonly seen respiratory infectious disease in clinical settings. If a child is at school and classmates have pertussis without antibodies in their body, it is quite possible for the infection to occur, commonly seen in babies under five years old. If there are episodes of spasmodic, convulsive coughing accompanied by a barking sound or a crowing sound during inhalation, this disease should be highly suspected, and prompt culturing of the pathogen is needed for confirmation.

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Written by Tong Peng
Pediatrics
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The difference between pertussis and allergic cough

Pertussis (whooping cough) and allergic cough are different. Firstly, pertussis is an acute respiratory infectious disease caused by Bordetella pertussis. Its symptoms include paroxysmal and frequent coughing, sometimes accompanied by a deep, crowing, inspiratory whoop sound. If not treated promptly, the condition can last for several months, which is why it is called whooping cough. Due to its high contagiosity and epidemic history, if infants contract pertussis, their condition can worsen, making them prone to complications like severe pneumonia or heart failure. However, allergic cough is a non-infectious condition primarily caused by hypersensitivity of the airways, easily triggered by various external allergens, leading to irritating dry coughs, but not worsening to lower respiratory tract infections. In daily life, by avoiding environmental allergens and using treatments such as nebulization and oral antiallergic medications, management is possible.

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Written by Li Jian Wu
Pulmonology
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What are the symptoms of whooping cough?

Pertussis, also known as whooping cough, typically manifests as paroxysmal coughing. During the acute phase, the cough is spasmodic, and some patients may produce sounds similar to a dog's bark or a rooster's crow. This type of cough can lead to complications such as a runny nose, tearing, facial flushing, red ears, and vomiting. Diagnosis should be confirmed through routine examination of secretions. During the acute phase, symptomatic treatment should be administered, along with the selection of macrolide antibiotics to eliminate the pathogenic bacteria, which are mostly due to infection by Corynebacterium diphtheriae or Bordetella pertussis. Patients should adjust their mindset, drink plenty of warm water, and maintain clean indoor air.

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Written by Li Jian Wu
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What are the symptoms of pertussis encephalopathy?

Pertussis encephalopathy typically presents with persistent high fever, projectile vomiting, nausea, and severe headaches, which are indicators of increased intracranial pressure. It is necessary to conduct timely auxiliary examinations such as cerebrospinal fluid tests and cranial MRI for diagnosis. In conjunction with clinical symptoms, medications to alleviate cerebral edema and reduce intracranial pressure should be chosen for symptomatic treatment. Typically, corticosteroids are needed during the acute phase, along with mannitol, sedatives, and other symptomatic treatments. Additionally, antibiotics should be used to eliminate the Bordetella pertussis bacterium, the pathogen responsible for the condition.