How is whooping cough treated?

Written by Li Jian Wu
Pulmonology
Updated on April 09, 2025
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Pertussis, also known as whooping cough, is an infectious respiratory disease caused by the infection of Bordetella pertussis or Bordetella parapertussis. Clinically, it is characterized by episodes of sudden, rapid coughing, a bark-like cough, and an inspiratory "crowing" sound. It is also advisable to check the sputum culture to confirm the cause of the disease. In terms of treatment, in addition to symptomatic treatment, macrolide antibiotics should be selected and administered for at least about half a month. Options include intravenous drips of erythromycin injection or azithromycin injection.

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Written by Li Jian Wu
Pulmonology
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How to diagnose the incubation period of pertussis

The incubation period of whooping cough generally has no autonomous discomfort symptoms. If there is close contact with a patient and the body lacks antibodies, suspecting the presence of this pathogen, corresponding auxiliary examinations can be conducted for diagnosis. Bacteriological examinations and fluorescent antibody methods can be performed, using nasopharyngeal swab secretions smear or nasal mucosa impression smear fluorescent antibody staining to detect specific antigens, with an early positive rate of 75%-85%. Complement fixation tests in serology can also be conducted to detect specific antibodies, effectively aiding in the diagnosis of atypical cases.

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Written by Li Jian Wu
Pulmonology
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Does whooping cough cause diarrhea?

Mild cases of pertussis, commonly known as whooping cough, generally do not cause diarrhea. Diarrhea is a symptom of the gastrointestinal tract, whereas whooping cough is a contagious respiratory disease caused by a common bacterial infection. It can lead to symptoms such as vomiting, nasal discharge, and tearing due to coughing. The typical symptoms include a cough that sounds like a bark or a crowing sound during inhalation. The main treatment principle is symptomatic treatment, thinning the mucus, and relieving bronchial smooth muscle spasms. During the acute phase, macrolide antibiotics such as erythromycin or azithromycin can be chosen for treatment. (Please use medication under the guidance of a doctor.)

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Written by Li Jian Wu
Pulmonology
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Can adult whooping cough heal itself?

Adults with pertussis, a condition that can resolve on its own if the symptoms are mild and the body's immune function is normal. However, decisions should be based on individual constitution, and not all patients can self-heal, especially those who are frail or have endocrine diseases generally cannot recover on their own. It is necessary to timely choose macrolide antibiotics and combine them with symptomatic treatment to alleviate symptoms such as cough, difficulty breathing, and fever. Regular exercise is needed to boost immunity.

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Written by Li Jian Wu
Pulmonology
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Pertussis and measles transmission pathways

Pertussis and measles are two types of diseases, both of which are respiratory infectious diseases. Pertussis is caused by Corynebacterium diphtheriae or Bordetella pertussis, while measles is an acute, infectious disease caused by the measles virus. Transmission mainly occurs through close contact with infected individuals and via airborne droplets, and it is commonly seen in infants and young children under the age of five. Prevention of these diseases is primarily through vaccination, and once the disease occurs, it is important to promptly treat the infection with anti-inflammatory or antiviral treatments, while also managing the symptoms accordingly.

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Written by Li Jian Wu
Pulmonology
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Is the pertussis vaccine a live vaccine?

The pertussis vaccine is a type of attenuated live vaccine, which clinically is mainly part of a combination vaccine that includes pertussis, diphtheria, and tetanus, commonly referred to as the DTP vaccine. Normally, a baby should receive the first dose at three months of age, followed by the second dose in the fourth and fifth months, as part of basic immunization. Between the age of eighteen months and two years, another dose is administered to boost immunity, which after producing lifelong antibodies, prevents reinfection with the disease.