Can you still get whooping cough even if you have been vaccinated?

Written by Li Jian Wu
Pulmonology
Updated on January 14, 2025
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If the whooping cough vaccine is administered effectively and antibodies are produced, it generally prevents reinfection. However, if the vaccine is not administered according to the prescribed schedule, or if no antibodies are produced after the vaccination, exposure to this pathogen may still lead to infection. The disease is characterized by fits of coughing, which can cause blushing, runny nose, tears, nausea, and vomiting. Some children may also experience a barking cough and a crowing sound during inhalation.

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Written by Li Jian Wu
Pulmonology
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Pertussis and measles transmission pathways

Pertussis and measles are two types of diseases, both of which are respiratory infectious diseases. Pertussis is caused by Corynebacterium diphtheriae or Bordetella pertussis, while measles is an acute, infectious disease caused by the measles virus. Transmission mainly occurs through close contact with infected individuals and via airborne droplets, and it is commonly seen in infants and young children under the age of five. Prevention of these diseases is primarily through vaccination, and once the disease occurs, it is important to promptly treat the infection with anti-inflammatory or antiviral treatments, while also managing the symptoms accordingly.

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Written by Li Jian Wu
Pulmonology
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What are the symptoms of whooping cough?

Pertussis has many symptoms. The early symptoms are the same as those of a common cold, including a runny nose, sore throat, and fever. About one to two weeks later, episodic, spastic coughing occurs. Some may also experience a barking cough and a crowing sound during inhalation, which are characteristic symptoms of pertussis. This type of cough can lead to complications such as an acute facial expression, redness in the face and ears, runny nose, tears, and vomiting. It is necessary to culture the pathogen and choose sensitive antibiotics to kill this bordetella pertussis.

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Written by Li Jian Wu
Pulmonology
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Is the pertussis vaccine a live vaccine?

The pertussis vaccine is a type of attenuated live vaccine, which clinically is mainly part of a combination vaccine that includes pertussis, diphtheria, and tetanus, commonly referred to as the DTP vaccine. Normally, a baby should receive the first dose at three months of age, followed by the second dose in the fourth and fifth months, as part of basic immunization. Between the age of eighteen months and two years, another dose is administered to boost immunity, which after producing lifelong antibodies, prevents reinfection with the disease.

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Written by Zeng Hai Jiang
Pediatrics
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How to determine whether it is the paroxysmal stage or the recovery stage of pertussis?

After the incubation period, typical whooping cough goes through three clinical stages. The first stage is the catarrhal stage, also called the pre-paroxysmal stage, during which the infectivity is the strongest. If treated promptly during this stage, the progress of the disease can be controlled. If the catarrhal stage is not effectively controlled, it then enters the paroxysmal stage. During the paroxysmal stage, the patient will experience episodic spasmodic coughing, with more severe episodes at night. During spasms, there will be neck vein distension, swollen and congested eyelids and face, and cyanosis of the lips. This stage can last up to two months. After the paroxysmal stage follows the convalescent stage, where the episodic spasmodic coughing gradually decreases and becomes less severe.

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Written by Li Jian Wu
Pulmonology
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Treatment methods for pertussis

For the treatment of whooping cough, the first step should be to drink plenty of water and maintain a suitable indoor temperature and humidity. In terms of medication, it is necessary to choose macrolide antibiotics and adhere to an inflammatory treatment course. Clinically common drugs include erythromycin, roxithromycin, azithromycin, clarithromycin, etc., and generally, medication is required for at least about ten days. At the same time, it is recommended to use antitussive and expectorant drugs. If there are symptoms of breathing difficulty, oxygen inhalation can also be administered. There are many expectorant drugs clinically available, such as carbocisteine or She Dan Chuan Bei liquid, ambroxol oral solution, etc., all of which can serve the function of suppressing coughs and expelling phlegm.