Childhood diarrhea is a common symptom in children, characterized by an increase in the frequency of bowel movements and unformed stools. Enema is a common treatment method in pediatric clinical practice, where the medication is absorbed through the rectal veins to achieve therapeutic effects. The medication used for the enema should be based on the cause of the child's diarrhea. For instance, if the diarrhea is due to indigestion, medications for indigestion should be used for the enema. If the stool is watery, astringent and antidiarrheal medications should be administered. If the child’s diarrhea is caused by enteritis due to inflammation, anti-inflammatory medications are required for the enema. If it is caused by a viral factor, antiviral medications should be used. Therefore, the specific medication for the diarrhea enema needs to be adjusted according to the actual symptoms of the child.